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Bioorganic Chemistry|October 29, 2021
Discovery of KRas G12C-IN-3 and Pomalidomide-based PROTACs as degraders of endogenous KRAS G12C with potent anticancer activityLing Li, Yinrong Wu, Zichao Yang, et al.Bioorganic Chemistry|February 10, 2022
Discovery of human hexosaminidase inhibitors by in situ screening of a library of mono- and divalent pyrrolidine iminosugarsValeria Pingitore, Macarena Martínez-Bailén, Ana T Carmona, et al.Bioorganic Chemistry|February 8, 2022
Identification of a promising hit from a new series of pyrazolo[1,5-a]pyrimidine based compounds as a potential anticancer agent with potent CDK1 inhibitory and pro-apoptotic properties through a multistep in vitro assessmentHossam R Elgiushy, Sameh H Mohamed, Heba Taha, et al.Bioorganic Chemistry|October 15, 2021
Guided rational design with scaffold hopping leading to novel histamine H3 receptor ligandsNakisa Ghamari, Saeed Kouhi Hargelan, Aleksandra Zivkovic, et al.Bioorganic Chemistry|October 21, 2021
Amberlyst-15 catalysed synthesis of novel indole derivatives under ultrasound irradiation: Their evaluation as serotonin 5-HT2C receptor agonistsGangireddy Sujeevan Reddy, Rajamanikkam Kamaraj, Kazi Amirul Hossain, et al.Bioorganic Chemistry|February 12, 2022
Comprehensive investigation of binding of some polycyclic aromatic hydrocarbons with bovine serum albumin: Spectroscopic and molecular docking studiesFatemeh Rostamnezhad, Mohammad Hossein FatemiBioorganic Chemistry|January 22, 2022
Enhanced antioxidation capacity endowed to a mixed type aldose reductase inhibitor leads to a promising anti-diabetic complications agentYuanlin Liu, Hui Mo, Kun Zhang, et al.Bioorganic Chemistry|January 23, 2022
In vitro absorption and lipid-lowering activity of baicalin esters synthesized by whole-cell catalyzed esterificationMengmeng Zhang, Xuan Xin, Guanglei Zhao, et al.Bioorganic Chemistry|January 25, 2022
Microwave assisted Biology-Oriented Drug Synthesis (BIODS) of new N,N'-disubstituted benzylamine analogous of 4-aminoantipyrine against leishmaniasis - In vitro assay and in silico-predicted molecular interactions with key metabolic targetsMuhammad Iqbal Choudhary, Fazila Rizvi, Hina Siddiqui, et al.Bioorganic Chemistry|January 26, 2022
Discovery of novel potent covalent inhibitor-based EGFR degrader with excellent in vivo efficacyShi Shi, Yu Du, Lei Huang, et al.Pageof 868