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Bioorganic Chemistry|October 28, 2025
Design, synthesis, and antitumor evaluation of new pyridazinone scaffolds as dual EGFR/VEGFR-2 kinase inhibitors and apoptotic cells inducersSara Y Ewieda, Eman M Ahmed, Nirvana A Gohar, et al.
Bioorganic Chemistry|October 28, 2025
Discovery of adamantane-based α-hydroxycarboxylic acid derivatives as potent M2-S31N blockers of influenza A virusJianghong Dong, Changjuan Chen, Xin Sun, et al.
Bioorganic Chemistry|November 7, 2025
Engineering of isoleucine dioxygenase for efficient multi-enzymatic cascade synthesis of (2S, 3R, 4S)-4-hydroxyisoleucineXinqi Xu, Xialian Wang, Lian Xu, et al.
Bioorganic Chemistry|November 7, 2025
Isolation and bioactivity evaluation of ten novel norlignans and additional neuroprotective compounds from Curculigo gracilisWei Ma, Xue-Ru Wang, Wen-Juan Niu, et al.
Bioorganic Chemistry|October 31, 2025
C-Prenylation of dihydrochalcones by prenyltransferases AnaPT and its engineered mutantsQi Zhou, Yanzhi Yang, Xia Yu, et al.
Bioorganic Chemistry|October 27, 2025
Design, synthesis and structure-activity relationship of 5'-prenylated chalcone derivatives inhibited the proliferation of human non-small cell lung cancer cells via inducing ferroptosisLong Zhao, Jie Chen, Meng-Fan Xu, et al.
Bioorganic Chemistry|October 24, 2025
Design, synthesis, and computational validation of novel benzothiazole derivatives as dual anticancer-antioxidant agents targeting VEGFR-2Fatma AlZahraa A A Mohamed, Dagmara Kłopotowska, Mohammed K Abd El-Gaber, et al.
Bioorganic Chemistry|October 22, 2025
Synthesis and in vitro inhibitory activity of N-arylsulfonamide adenosine analogues designed to target SARS-CoV-2 nsp14 N7-methyltransferaseMarcel Hausdorff, Adrien Delpal, Hugo Machin, et al.
Bioorganic Chemistry|October 28, 2025
The emerging role of Oxadiazole derivatives as VEGFR and EGFR inhibitors in Cancer therapyRajarshi Nath, Biplab Debnath, Anhic Chakraborty, et al.
Bioorganic Chemistry|October 25, 2025
Synthesis and evaluation of 8-(benzyloxy)-5,7-dibromo-2-methylquinoline derivatives as inducers of apoptosis in triple-negative breast cancer MDA-MB-468 cells via MKK7-JNK pathway activationLiang Ma, Shizhun Zhang, Xiuping Mao, et al.
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