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Bioorganic Chemistry|July 29, 2025
Discovery of a ubiquitin-specific protease 10 inhibitor with high binding affinity promoting cell apoptosis via down-regulated CDK4 for the treatment of hepatocellular carcinomaYang Lu, Wentao Wang, Cheng Yuan, et al.
Bioorganic Chemistry|July 23, 2025
Rationally designed small peptides targeting DPP-4: Identification of potent anti-diabetic agentsSombir Jaglan, Palwinder Singh, Sheetal Vermani, et al.
Bioorganic Chemistry|July 27, 2025
Inhibitory activity of amino acid derivatives against native Cryptococcus neoformans urease and ligand-enzyme binding profile by nuclear Paramagnetic Relaxation Enhancement and Saturation Transfer Difference NMRDanilo H Carlo, Paulo Henrique Guilherme Borges, Sueli Fumie Yamada-Ogatta, et al.
Bioorganic Chemistry|July 25, 2025
Mechanism of sulforaphane in treatment of pancreatic cancer cell based on network pharmacology and in vitro experimentsZiyi Ren, Jiahui Feng, Meng Yang, et al.
Bioorganic Chemistry|July 24, 2025
Therapeutic applications and molecular mechanisms of TNIK inhibitors: A comprehensive review of current advancesYating Li, Fuyu Wang, Kexin Wang, et al.
Bioorganic Chemistry|July 24, 2025
Isolation, characterization, and biological evaluation of bioactive components from the stem bark of Broussonetia papyrifera: Antioxidant properties and apoptosis induction in breast cancer cellsCai-Wei Li, Sin-Min Li, Jih-Jung Chen
Bioorganic Chemistry|July 24, 2025
Discovery and synthesis of azepinoindoles as novel hCYP1B1 inhibitors with AhR-independent anticancer activityJiang Wang, Sheng-Nan Wang, Jue Guo, et al.
Bioorganic Chemistry|July 24, 2025
Dual α-amylase and α-glucosidase inhibitors: recent progress from natural and synthetic resourcesRitesh Jha, Kamya Goyal, Sidharth Mehan, et al.
Bioorganic Chemistry|June 27, 2025
Design, synthesis and biological evaluation of 2-phenylquinoxaline carbonyl piperazine derivatives as novel FASN inhibitors with anticancer activityShailendra Singh, Subarno Paul, Fábio G Martins, et al.
Bioorganic Chemistry|July 16, 2025
Discovery of imidazo[1,2-b]pyridazine derivatives as potent TRK inhibitors for overcoming multiple resistant mutantsYunsheng Xu, Wei Zhao, Zhenghai Wang, et al.
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