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Bioorganic Chemistry|September 9, 2023
A New Avenue for Enhanced Treatment of Hyperuricemia and Oxidative Stress: Design, Synthesis and Biological Evaluation of Some Novel Mutual Prodrugs Involving Febuxostat Conjugated with Different AntioxidantsAya Y Rashad, Hoda G Daabees, Mohamed Elagawany, et al.
Bioorganic Chemistry|September 6, 2023
Design, synthesis and bioactivity evaluation of selenium-containing PI3Kδ inhibitorsLi Gao, Hongyan Chuai, Mengyan Ma, et al.
Bioorganic Chemistry|September 1, 2023
Novel photoactivated Indole-pyridine chemotherapeutics with strong antimicrobial and antibiofilm activity toward Staphylococcus aureusZhishang Zhang, Wenqing Li, Haorui Wu, et al.
Bioorganic Chemistry|August 31, 2023
Synthesis and clinical application of small-molecule inhibitors and PROTACs of anaplastic lymphoma kinaseHua Gao, Jing-Yi Zhang, Li-Jie Zhao, et al.
Bioorganic Chemistry|August 23, 2023
Molecular overlay-guided design of new CDK2 inhibitor thiazepinopurines: Synthesis, anticancer, and mechanistic investigationsEbtehal M Husseiny, Hamada S Abulkhair, Asmaa Saleh, et al.
Bioorganic Chemistry|August 18, 2023
Design, synthesis and anti-tumor efficacy evaluation of novel 1,3-diaryl propane-based polyphenols obtained from Claisen rearrangement reactionSong-Wei Jiang, Xiang Qi, Haowen Deng, et al.
Bioorganic Chemistry|August 18, 2023
Development of novel HEPT analogs featuring significantly improved anti-resistance potency against HIV-1 through chemical space exploration of the tolerant region IRuo-Lan Zhou, Christophe Pannecouque, Erik De Clercq, et al.
Bioorganic Chemistry|August 16, 2023
BCL11A-targeted γ-globin gene induction by triterpenoid glycosides of Fagonia indica: A preclinical scientific validation of indigenous herb for the treatment of β-hemoglobinopathiesFizza Iftikhar, Muhammad Behroz Naeem Khan, Syeda Tehreem, et al.
Bioorganic Chemistry|August 13, 2023
Total syntheses and antibacterial evaluations of cudraflavones A-C and related FlavonesHongbo Dong, Li Liao, Pei Yu, et al.
Bioorganic Chemistry|August 10, 2023
Structure-based drug design, synthesis, and biological evaluation of novel 1,3,5-triazine or pyrimidine derivatives containing benzoyl hydrazine moiety as PI3Kα selective inhibitorsSiyu Fu, Jiuyu Liu, Chunting Li, et al.
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