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Bioorganic Chemistry|December 26, 2023
Advances in synthesis and biological evaluation of CDK2 inhibitors for cancer therapyDharmesh A Patel, Siddharth S Patel, Hitesh D Patel
Bioorganic Chemistry|December 16, 2023
Design, synthesis, and biological evaluation of novel capsaicin-tacrine hybrids as multi-target agents for the treatment of Alzheimer's diseaseJuanyue Long, Fengxue Qin, Jinchong Luo, et al.
Bioorganic Chemistry|December 14, 2023
Computational Design, Synthesis, and Bioevaluation of 2-(Pyrimidin-4-yl)oxazole-4-carboxamide Derivatives: Dual Inhibition of EGFRWT and EGFRT790M with ADMET ProfilingNilesh Raghunath Khedkar, Milind Sindkhedkar, Alex Joseph
Bioorganic Chemistry|December 20, 2023
Pathology, target discovery, and the evolution of XO inhibitors from the first discovery to recent advances (2020-2023)Nitish Kumar, Komalpreet Kaur, Navjot Kaur, et al.
Bioorganic Chemistry|November 30, 2023
Synthesis and application of clinically approved small-molecule drugs targeting androgen receptorHua Gao, Jing-Yi Zhang, Li-Jie Zhao, et al.
Bioorganic Chemistry|November 30, 2023
Discovery of a near-infrared fluorescent probe for G-quadruplexes by exploiting the concept of unfolding-intramolecular-aggregation-induced emissionXiao-Dong Wang, Yong-Si Liu, Ming-Hao Hu
Bioorganic Chemistry|December 6, 2023
Design, synthesis, and biological evaluation of novel donepezil-tacrine hybrids as multi-functional agents with low neurotoxicity against Alzheimer's diseaseNingwei Wang, Wenlong Jia, Junqin Wang, et al.
Bioorganic Chemistry|November 25, 2023
Design, synthesis, and biological evaluation of novel tryptanthrin derivatives as selective acetylcholinesterase inhibitors for the treatment of Alzheimer's diseaseJucheng Xia, Shuanghong Dong, Lili Yang, et al.
Bioorganic Chemistry|November 25, 2023
In situ interaction between the hormone 17α-ethynylestradiol and the liquid-ordered phase composed of the lipid rafts sphingomyelin and cholesterolGilia Cristine Marques Ruiz, Luis Fernando do Carmo Morato, Wallance Moreira Pazin, et al.
Bioorganic Chemistry|November 23, 2023
N-(3-Methoxyphenyl)-6-(7-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl)pyridin-2-amine is an inhibitor of the FLT3-ITD and BCR-ABL pathways, and potently inhibits FLT3-ITD/D835Y and FLT3-ITD/F691L secondary mutantsXiuqi Wang, Rosa Anna DeFilippis, Yuet-Kin Leung, et al.
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