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Bioorganic Chemistry|April 21, 2026
Synthesis of desloratadine analogues as potent antifungal agents: in vitro and in vivo efficacy, and structure-activity relationship studiesShoukat Wali, Farzeen Ghazal, Atia-Tul-Wahab, et al.
Bioorganic Chemistry|April 19, 2026
Design and synthesis of novel isatin-isoniazidhydrazone hybrid-based 1,2,3-triazoles as dual EGFR/PARP-1 inhibitors and apoptosis inducers in breast cancer cellsMuna A Alshams, Mohamed S Nafie, Anil Ravi, et al.
Bioorganic Chemistry|April 19, 2026
New nonacyclic duclauxin derivatives with potent anti-influenza activities from Antarctic fungus Penicillium sp. CPCC 401065Qingrong Du, Zhe Guo, Yujia Wang, et al.
Bioorganic Chemistry|April 19, 2026
Synthesis, biological evaluation, and mechanism investigation of multisubstituted quinazoline analogues as prospective inhibitors of KRAS G12DXiu-Juan Liu, Qiuying Nie, Yao-Sheng Zhang, et al.
Bioorganic Chemistry|April 22, 2026
Green and sustainable approaches towards synthesis of anticancer bioheterocycles via microwave irradiationShivani, Khushi Sharma, Sandeep Chaudhary
Bioorganic Chemistry|April 23, 2026
Fragment-based discovery of pyrazole-5-carboxamide derivatives as ALK inhibitors against non-small cell lung cancerHong-Ye Liu, Yan-Ping Wang, Ying-Hao Sun, et al.
Bioorganic Chemistry|April 23, 2026
Assessment of the antimicrobial properties of novel azopyrazolo[1,5-a]pyrimidine derivatives targeting DNA gyrase enzyme: design, synthesis, and molecular docking studiesRehab Sabour, Amel S Younes, Shimaa M Abd El-Gilil, et al.
Bioorganic Chemistry|April 26, 2026
Pyridinium quaternary ammonium disinfectants inhibit neurosteroid biosynthesis as human and rat 5α-reductase 1 inhibitorsXueting Li, Yinghao Huang, Jiansong Zhou, et al.
Bioorganic Chemistry|April 26, 2026
The novel PDE5 inhibitor CPD1 attenuates pulmonary arterial hypertension through dual modulation of cGMP and TRPM8-mediated pathwaysYunping Mu, Jinlin Sun, Xindan Zhang, et al.
Bioorganic Chemistry|April 26, 2026
Design, synthesis, and anti-inflammatory evaluation of novel N-(Benzol[d]oxazol-5-yl)sulfonamides as NLRP3 inflammasome inhibitorsZhendi Shi, Leyan Wang, Jiayue Huang, et al.
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