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Bioorganic Chemistry|June 23, 2026
From local anesthetics to antibacterial agents: design, synthesis, and activity evaluation of dyclonine quaternary ammonium salt derivativesLinyuan Zhu, Yuqian Kan, Yawei Zhang, et al.
Bioorganic Chemistry|June 23, 2026
Unexpected vanillin derivatives featuring a 1,3-dithiol fragment via CC bond formation: Synthetic pathways, molecular docking, ADME-Tox, molecular dynamics simulation and antimicrobial activitiesTakoua Belghit, Lotfi Bourogaa, Leila Boukaous, et al.
Bioorganic Chemistry|June 24, 2026
Rosmarinic acid attenuates hyperuricemia-induced intestinal damage by activating mitophagy via the p38 MAPK/mTOR pathwayJian Guo, Meihan Zhang, Yuanhang Cheng, et al.
Bioorganic Chemistry|June 26, 2026
Microwave-assisted green synthesis and biological evaluation of a novel isatin-thiazole-benzofuran hybrid with dual acetylcholinesterase inhibitory and antioxidant activitiesEslam M Lotfy, Israa A Seliem
Bioorganic Chemistry|June 18, 2026
Exploiting siderophores and related proteins for antimicrobial strategies in Staphylococcus aureus: A reviewSung-Min Kang, Song-A Lee, Seoyoung Choi, et al.
Bioorganic Chemistry|June 20, 2026
A binding-depth-dependent continuum of ADAM17/TACE inhibition revealed by punicalagin-derived polyphenolsMukhammad Asy'ari, Ariztha Delivia Putri, Rinjani Ayundatika Putri, et al.
Bioorganic Chemistry|June 20, 2026
Divergent roles of active-site and access-channel residues in controlling regioselectivity and catalytic efficiency in CYP154C10Prakash Paudel, Kamal Prasad Regmi, Ki-Hwa Kim, et al.
Bioorganic Chemistry|June 19, 2026
Discovery of selective CDK9 degraders with anti-AML activity using PROTAC technologyQing Li, Fuyuan Zhou, Ding Luo, et al.
Bioorganic Chemistry|June 19, 2026
Discovery of furan-trimethoxyphenyl hybrids as novel colchicine-binding site inhibitors that induce mitotic catastrophe with potent anti-acute myeloid leukemia effectPeng Tan, Xuejiao Wei, Longyan Wang, et al.
Bioorganic Chemistry|June 27, 2026
Complex phloroglucinols from glandular hairs of Mallotus philippensis and their antiviral activitiesWenlin Zheng, Changli Sun, Qiuyi Luo, et al.
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