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Bioorganic Chemistry|June 29, 2026
Novel 2-indolinone benzylpiperidine- thiosemicarbazone hybrids as cholinesterase inhibitors: Design, synthesis and biological evaluationZekiye Şeyma Sevinçli, Özge Soylu-Eter, Gozde Hasbal-Celikok, et al.
Bioorganic Chemistry|June 29, 2026
Discovery of indolyl-urea compounds as effective STING PROTAC degraders for the treatment of acute kidney injuryPeng Zhou, Yaya Peng, Tingting Zhang, et al.
Bioorganic Chemistry|June 30, 2026
Noninvasive deciphering of the immunosuppressive tumor microenvironment and evaluation of MerTK inhibitor mediated reversal of ICB resistance via MerTK-targeted PETYunyi Yang, Jinghui Qin, Xiaobing Tang, et al.
Bioorganic Chemistry|July 1, 2026
Characterization and engineering of a fungal unspecific peroxygenase for aliphatic CH hydroxylationFikri A R H Oktavia, Jun-Hong Kim, Ji-Ae Mok, et al.
Bioorganic Chemistry|June 17, 2026
Design, synthesis, and biological evaluation of clovamide analogues as anti-colitis agents modulating NF-κB/STAT3/iNOS signalingMojahid Mohammed Khalid Elnur, Kiran Yadav, Kalpana Ghimire, et al.
Bioorganic Chemistry|June 18, 2026
Exploring the competitive inhibition mechanism of α-glucosidase by metforminMiaomiao Tian, Chengrui Xiao, Yanan Wei, et al.
Bioorganic Chemistry|June 19, 2026
Functionalized thiazole and thiophene compounds as aldose reductase inhibitors: from rational design to biological and in silico evaluationHeba M Metwally, Mariam M Kiwan, Bakr F Abdel-Wahab, et al.
Bioorganic Chemistry|June 18, 2026
Integrated screening and identification of potent lactate dehydrogenase inhibitors from Abrus cantoniensis and Abrus mollis via affinity ultrafiltration and molecular simulationsYuwei Lu, Quanxin Li, Wenwen Luo, et al.
Bioorganic Chemistry|July 3, 2026
Synthesis and biological evaluation of C6-modified Celastrol derivatives as anti-inflammatory agents targeting the NF-κB signaling pathwayHao-Ran Yang, Jun-Xia Wang, Long-Long Jin, et al.
Bioorganic Chemistry|July 2, 2026
Structure-guided modulation of the IL-4/IL-4Rα interface: molecular recognition, therapeutic antibodies, and small-molecule opportunitiesRuijie Jiao, Lisha Liang, Erkang Tian, et al.
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