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Bioorganic Chemistry|July 10, 2026
Targeting ALOX12: design, synthesis, and anti-inflammatory mechanism study of linker-free PROTAC moleculesXiaolan Li, Sitian Shen, Chaoqin Duan, et al.
Bioorganic Chemistry|July 10, 2026
Virtual screening-guided repurposing of fluorescent probes to detect EGFR expression in renal cellsGiovanni Graziano, Daniela Trisciuzzi, Marialessandra Contino, et al.
Bioorganic Chemistry|July 11, 2026
Rationally designed phytochemical-derived carbamate hybrids unveiling potent inhibition of cholinesterase and amyloid-β peptidesAruna Ghose, Sudhir Kumar Paidesetty, Shakti Ketan Prusty, et al.
Bioorganic Chemistry|July 10, 2026
Insights into novel benzo[h]quinoline-based 2-thioxothiazolidin-4-one and thiazol-4-one hybrids as potential antimicrobial, and antibiofilm candidates: Design, synthesis, molecular modeling, and in-silico ADME studiesReham R Raslan, Sally I Eissa, Moustafa S Abusaif, et al.
Bioorganic Chemistry|July 9, 2026
Structure-activity relationship analysis of a Pyrrolo-Phenylamidine scaffold as a chemotype for ubiquitin-specific protease 11 (USP11) inhibitionSoomin Kang, Jihwan Yoon, Sunghoon Hurh, et al.
Bioorganic Chemistry|July 9, 2026
Enhanced oral absorption and anti-colorectal cancer efficacy of trifluridine by interfering with both TPase and UPaseShulin Wan, Xinyi Fan, Peng Jin, et al.
Bioorganic Chemistry|July 6, 2026
Cytotoxic indole diterpenoids from the fungus Aspergillus pseudonomius: isolation, structural elucidation, and biological evaluationXiliang Yang, Rui Chen, Long Chen, et al.
Bioorganic Chemistry|July 8, 2026
Identification of novel pyrazolines and isoxazolines as antileishmanial agents via a potential antifolate mechanism: synthesis, biological evaluation, and in silico studiesMenna Desouky, Menna S Hany, Ahmed R Elaraby, et al.
Bioorganic Chemistry|July 8, 2026
At the crossroads of senescence and immunosuppression: Machine learning and multi-omics unveil the central role of FAP in HNSCCJingyu Zhang, Zhan Yang, Zhixu He, et al.
Bioorganic Chemistry|March 26, 2026
Cyclic peptide-decorated PtIV-DCA prodrug triggers ferroptosis in glioblastoma via the disruption of energy metabolismHaisheng Liu, Chenyao Feng, Miaoshui Guan, et al.
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