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Bioorganic Chemistry|August 10, 2026
Genome mining and metabolomics unveil new napyradiomycin antibiotics from Streptomyces sp. 0H2MMin Wang, Nuo Chen, Qichen Zhang, et al.
Bioorganic Chemistry|August 10, 2026
Heterostructure engineering of Au@UiO-67-bpy(Cu)/MoS2 cascade nanozymes for self-fueled and NIR-enhanced chemodynamic/photothermal cancer therapyUmarov Abdusalom, Kasimova Gulnora, Alikulova Hakima, et al.
Bioorganic Chemistry|August 10, 2026
Alkaloids from the nearly ripe fruits of Tetradium ruticarpum and inhibitory effects on colorectal cancer cellsPing Guo, Yuanyuan Li, Jianming Yu, et al.
Bioorganic Chemistry|August 17, 2026
Discovery of 3-[(5-nitro-2-heteroaryl)methylene]-2-indolinone derivatives as highly potent antileishmanial agents and their bioactivation by NTR1 and 2Seyyed Hasan Shariatmadari, Marta Lopes Lima, Rachel Milne, et al.
Bioorganic Chemistry|August 15, 2026
Recent advances in synthetic strategies of fourth-generation EGFR tyrosine kinase inhibitors under clinical trials for the treatment of resistant non-small cell lung cancer (NSCLC)Vaibhav M Kadam, Harun M Patel
Bioorganic Chemistry|August 18, 2026
Novel VHL ligand-based PROTACs targeting JNK1: design, synthesis, and biological evaluation with potent anti-EMT activityShuhua Ren, Ye Zhang, Rui Hao, et al.
Bioorganic Chemistry|August 18, 2026
Deep learning-driven discovery and optimization of natural LSD1 inhibitors for the treatment of Alzheimer's diseaseZhonghua Li, Tiancheng Sun, Mengyu Han, et al.
Bioorganic Chemistry|August 18, 2026
Design, synthesis and biological evaluation of novel 1,3,5-triazine derivatives containing benzo[d]imidazole scaffold as PI3K inhibitorsJu Liu, Nan Li, Runqi Zhang, et al.
Bioorganic Chemistry|August 22, 2026
Green synthesis of N-aryl-1-(2-bromo-4-methyl phenyl)-1H-tetrazol-5-amines as novel anti-cancer agents targeting tubulin-Combretastatin A4 complex and human non-small cell lung cancer cell linesUma Ravi Sankar Arigala, Raju Vasantham, Santhosh Kumar Nadikatla, et al.
Bioorganic Chemistry|August 22, 2026
Scutellarin as a specific GEN1 inhibitor synergizes with olaparib to induce synthetic lethality in human tumor cellsBinbin Zhan, Yichen Zhong, Xuening Chen, et al.
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