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Bioorganic Chemistry|March 21, 2022
Novel third-generation pyrimidines-based EGFR tyrosine kinase inhibitors targeting EGFR T790M mutation in advanced non-small cell lung cancerBaijiao An, Jian Liu, Yangyang Fan, et al.
Bioorganic Chemistry|April 11, 2022
Discovery of benzo[d]isothiazole derivatives as novel scaffold inhibitors targeting the programmed cell death-1/programmed cell death-ligand 1 (PD-1/PD-L1) interaction through "ring fusion" strategyYinli Gao, Hanxun Wang, Lanlan Shen, et al.
Bioorganic Chemistry|March 28, 2022
Benzoselenoates: A novel class of carbonic anhydrase inhibitorsDamiano Tanini, Antonella Capperucci, Maria Locuoco, et al.
Bioorganic Chemistry|March 31, 2022
Apoptosis induction, PARP-1 inhibition, and cell cycle analysis of leukemia cancer cells treated with novel synthetic 1,2,3-triazole-chalcone conjugatesEsraa M Othman, Eman A Fayed, Ebtehal M Husseiny, et al.
Bioorganic Chemistry|October 16, 2021
Design, synthesis and biological evaluation of cinnamamide-quinazoline derivatives as potential EGFR inhibitors to reverse T790M mutationBin Zhang, Zichen Xu, Qingqing Liu, et al.
Bioorganic Chemistry|October 15, 2021
Discovery of quinazolinyl-containing benzamides derivatives as novel HDAC1 inhibitors with in vitro and in vivo antitumor activitiesZixue Zhang, Qingwei Zhang, Hao Zhang, et al.
Bioorganic Chemistry|October 19, 2021
Caesalpinaxin, a cassane-type diterpenoid with a 21-carbon core skeleton from the seeds of Caesalpinia minax possessing pro-angiogenetic propertyRuohan Lou, Fan Xu, Yunshao Xu, et al.
Bioorganic Chemistry|September 18, 2018
Bioactive seco-abietane rearranged diterpenoids from the aerial parts of Salvia prionitisLingnan Li, Miaomiao Zhou, Guimin Xue, et al.
Bioorganic Chemistry|September 25, 2018
Chemically induced degradation of CK2 by proteolysis targeting chimeras based on a ubiquitin-proteasome pathwayHong Chen, Feihong Chen, Nannan Liu, et al.
Bioorganic Chemistry|September 1, 2018
Identification of novel and selective non-peptide inhibitors targeting the polo-box domain of polo-like kinase 1Yanhong Chen, Zhiyan Li, Yu Liu, et al.
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