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Bioorganic Chemistry|June 6, 2025
Exploitation of novel pyrazolo[3,4-d]pyrimidine scaffold tethered to thiazole as potential EGFR/HER2 dual kinase inhibitor to overcome lapatinib resistant breast cancer: Design, synthesis, in silico docking and molecular dynamic simulationIbrahim M Salem, Osama I El-Sabbagh, Samia M Mostafa, et al.
Bioorganic Chemistry|October 9, 2025
Novel dihydropyridines as potential calcium-channel and P-glycoprotein blockers applicable for chemotherapy sensitizationGang Chen, Shiyi Zhong, Chunxu Zhong, et al.
Bioorganic Chemistry|October 11, 2025
Apigenin and its derivative modulate nitric oxide production and interfere with TLR4-M2: In-vitro and in-silico insightsSamreen Soomro, M Ahmed Mesaik, Farzana Shaheen, et al.
Bioorganic Chemistry|October 8, 2025
Natural diterpenoids isolated-interaction-phenotypic target characterization: An idea performed with Daphne genkwa and Wikstroemia chamaedaphne bud extractShi-Fei Li, De-Ling Chen, Ya-Ting Li, et al.
Bioorganic Chemistry|October 10, 2025
Utility of carbon dots for diabetes treatment and management: A mini reviewNeha Sharma, Anshul Sharma, Hae-Jeung Lee
Bioorganic Chemistry|October 7, 2025
Hecogenin‑nitrogen mustard hybrids with improved anti-breast cancer activity: Design, synthesis, and biological evaluationWenle Su, Xiaoying Huang, Xinyuan Ji, et al.
Bioorganic Chemistry|October 7, 2025
Isolation and identification of Garciyunnanensisin A-O from Garcinia yunnanensis: a study on its antibacterial activity and mechanism against Staphylococcus aureusPeng-Xue Ji, Zhi-Yuan Li, Sheng-Nan Yang, et al.
Bioorganic Chemistry|November 4, 2025
BACH1 promotes hepatocellular carcinoma progression by targeting PDP1 towards the PI3K-AKT-mTOR signaling activationQiqi Bu, Xiaojing Qi, Qing Wang, et al.
Bioorganic Chemistry|November 12, 2025
Design, synthesis, and evaluation of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole-2-carboxamide derivatives as anti-HCC agents targeting Nur77Shengwei Hu, Xiaodan Li, Mingyue Yu, et al.
Bioorganic Chemistry|November 12, 2025
Design, synthesis, and biological evaluation of a bioavailable EZH2 PROTAC with a 2,8-diazaspiro[4.5]decane linkerWei Wei, Tianqiong Yang, Ziqiao Zhao, et al.
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