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Bioorganic Chemistry|December 20, 2025
Piperidine-based small molecules as dual-stage antileishmanial agents targeting parasite folate pathwayTarfah Al-Warhi, Haytham O Tawfik, Nermeen M Rashad, et al.Bioorganic Chemistry|December 23, 2025
Structural hybridization as a tool for developing novel biologically active analogues of protulactone ASanja Djokić, Mirjana Popsavin, Slađana Stanisavljević, et al.Bioorganic Chemistry|December 28, 2025
Zinc(II)-berberine-based complexes targeting mitochondria exhibit enhanced antiproliferative activity as single drugs or in combination with ABT-199Zhen-Feng Wang, Xiao-Qiong Huang, Run-Chun Wu, et al.Bioorganic Chemistry|December 28, 2025
Temporin-derived peptides promote MRSA-infected wound healing and protect mice from MRSA-induced pneumoniaXiao Jin, Yawen Lan, Rong Wang, et al.Bioorganic Chemistry|December 23, 2025
Herbacetin alleviates Parkinson's disease by inhibiting ferroptosis in PC12 cells through the Nrf2/GPX4 pathwayYu Liu, Yaru Wang, Junmin Xi, et al.Bioorganic Chemistry|December 21, 2025
Research progress of drugs targeting GPC3 in cancer therapyYe-Qin Li, Yuan Liao, Wen Zhang, et al.Bioorganic Chemistry|December 19, 2025
Dual topoisomerase IIα/EGFR-TK inhibitors: Synthesis, biological evaluation, and in silico studies of new thiadiazolo[3,2-a]pyrimidinone derivatives as potential anticancer agentsNayera I Mansour, Mariam A Ghaly, Nadia S El-GoharyBioorganic Chemistry|December 19, 2025
Design, synthesis, and biological evaluation of Benzimidazole-Aminopyrimidine hybrids as selective P38α MAPK inhibitors targeting Neuroinflammation in an AlCl3-induced rat model of Alzheimer's diseaseMohamed Samir, Nader E Abo-Dya, Nehal M Elsherbiny, et al.Bioorganic Chemistry|December 20, 2025
Design, synthesis, and characterization of metal-based N-heterocyclic carbene complexes for potential pharmaceutical applicationsMehwish Javed, Muhammad Adnan Iqbal, Ijaz Ahmad Bhatti, et al.Bioorganic Chemistry|December 18, 2025
Bioactive fractions of Swertia species protect myotubes and improve insulin sensitivity by regulating myogenic factors in differentiated skeletal muscle cellsKm Swati, Abhishek Goel, Shweta Sharma, et al.Pageof 868