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Bioorganic Chemistry|December 16, 2025
Bioengineered vancomycin-loaded chitosan/collagen nanocomposite from Sphyrna lewini: Antioxidant, antimicrobial, and antidiabetic applications in wound healingK Netha, R Karthick Raja, U Nithya, et al.
Bioorganic Chemistry|December 18, 2025
Discovery of a dual-target CRBN-mediated degrader for IKZF1/3 and GSPT1 proteinsChunchao Tang, Zhen Li, Ruiqiang Lu, et al.
Bioorganic Chemistry|December 20, 2025
Dimethyl bisphenolate inhibits glioblastoma growth by promoting cell cycle arrest and apoptosisRunpeng Chen, Mingtao Hao, Mengke Liu, et al.
Bioorganic Chemistry|January 13, 2026
Discovery of Calenduloside E (CE) and its derivatives as the glycolytic enzyme phosphoglycerate kinase 1 (PGK1) inhibitors for suppressing atherogenesisHuiqi Fang, Fang Han, Shan Wang, et al.
Bioorganic Chemistry|January 13, 2026
A dual-targeting antimicrobial agent: Discovery and mechanism of action of a novel 7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine compoundWeiqing He, Yajing Tian, Ke Li, et al.
Bioorganic Chemistry|February 7, 2026
Integrating synthesis, pharmacological evaluation, and molecular dynamics simulation of novel 8-substituted theophylline hybrids as potential PDE-4B inhibitors, bronchodilators and antibacterialTaha F S Ali, Marina A O Yani, Ibrahim M Salem, et al.
Bioorganic Chemistry|December 15, 2025
Novel bis-Thiazolidinone -based chalcones with pyridine linker: Eco-friendly synthesis, cholinesterase and beta-amyloid inhibition potency, and molecular docking studiesSobhi M Gomha, Sami A Al-Hussain, Sayed M Riyadh, et al.
Bioorganic Chemistry|April 30, 2025
Study of tamoxifen derived perfluoroalkylated olefins in breast cancer treatmentWojciech Chaladaj, María C Arufe, Fátima Lucio-Martínez, et al.
Bioorganic Chemistry|April 30, 2025
Precise structure manipulation of selective estrogen receptor modulators led to first-in-class thiophene-3-benzamide derivatives as potential ER-antagonists without uterotrophic activityBader Huwaimel, Amr S Abouzied, Abdul-Hamid Emwas, et al.
Bioorganic Chemistry|April 29, 2025
A novel hydroxytyrosol derivative HT-3 enhances antioxidant and neuroprotective activity through efficient molecular conjugationLinjie Zhang, Haopai Wei, Taihe Han, et al.
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