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Bioorganic Chemistry|April 5, 2025
Peptidomimetics based on thiacalixarene with L-tyrosine moieties: Antibacterial activity against methicillin-resistant Staphylococcus aureus and degradation induced by binding to α-chymotrypsinOlga Terenteva, Olga Mostovaya, Mikhail Bukharov, et al.
Bioorganic Chemistry|April 2, 2025
Novel p-terphenyls with anti-neuroinflammatory activity from fruiting bodies of the Chinese edible mushroom Thelephora ganbajun ZangHang Zhang, Jingyi Zhang, Keyin Huang, et al.
Bioorganic Chemistry|April 18, 2025
The diphenylpyrimidine derivative as a novel HDAC6 inhibitor alleviates atopic dermatitis through anti-inflammatory effects facilitated via TLR4/MAPK, STAT3 and NF-κB pathwaysJin-Ting Chen, Hao Qiu, Xin-Xin Ran, et al.
Bioorganic Chemistry|May 21, 2025
Lysosome-specific fluorescent probe for malondialdehyde/formaldehyde detection in oxidative/carbonyl stressed nerve cells and foodsXueting Liu, Zilu Li, Ziyi Wang, et al.
Bioorganic Chemistry|May 18, 2025
Design, synthesis, docking, DFT, and MD simulation studies of new piperazine, 1,3,4-oxadiazole, and quinoline conjugates: A search for potent antiepileptic agentsShrishti Tripathi, Rajnish Kumar, Abhijit Debnath, et al.
Bioorganic Chemistry|May 14, 2025
Site-selective structural modification of toosendanin enables one-step synthesis of 12-hydroxyamoorastatin: A natural tautomeric antitumor lead with low toxicityQing-Yan Cheng, Chen Yang, Yu-Ting Liao, et al.
Bioorganic Chemistry|May 15, 2025
Enhancing indican production in Escherichia coli through a multi-faceted experimental strategyJianianhua Luo, Jiahui Xu, Qi Li, et al.
Bioorganic Chemistry|May 13, 2025
Discovery of (E)-2-cyano-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)-3-(1H-indol-3-yl)acrylamide as a novel TDO inhibitor for cancer treatmentXiang Wang, Xiaoshuang Wang, Xiaoxue Wang, et al.
Bioorganic Chemistry|May 11, 2025
Integrating untargeted metabolomics and computational docking for biomarker evaluation: A case study on marine algae-derived ligandsHamada A A Noreldeen, Abdel-Rahman M Hamed, Mohamed El-Shazly, et al.
Bioorganic Chemistry|May 11, 2025
Design, synthesis and biological evaluation of novel 4,6-dimorpholino-1,3,5-triazin-2-amine ferrocenecarboxylate derivatives as potent PI3K inhibitorsYujue Wang, Haifeng Xu, Shiwen Yu, et al.
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