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Bioorganic Chemistry|November 8, 2025
Substituted chalcones inhibit biofilm formation and efflux pumps of multidrug resistant Staphylococcus aureus: Antimicrobial, molecular docking, ADME and QSAR studiesCedric Dzidzor Amengor, Patrick Gyan, Prince Danan Biniyam, et al.
Bioorganic Chemistry|November 8, 2025
Design and development of potent roflumilast analogues targeting PDE-4B: selectivity and pharmacokinetic insightsAhmed M Moussa, Heba Abdelrasheed Allam, Ahmed A Al-Karmalawy, et al.
Bioorganic Chemistry|November 6, 2025
PDL1-inhi.predictor: a two-tiered machine learning framework for predicting and prioritizing PDL1 inhibitorsHuiyan Ying, Junting Liu, Weikaixin Kong, et al.
Bioorganic Chemistry|November 1, 2025
In vitro and in vivo studies on three new 8-hydroxyquinoline-based zinc(II) coordination compounds as potential antimelanoma cancer agentsQing Su, Li-Lin Jiang, Qiu-Ming Li, et al.
Bioorganic Chemistry|November 12, 2025
Reversing the Warburg effect: Discovery of potent pyruvate dehydrogenase kinase inhibitors for inhibiting tumor growthMeiyan Tang, Yiyang Li, Pengju Ye, et al.
Bioorganic Chemistry|November 12, 2025
Newly synthesized pyranopyrazole nicotinamides derivatives as potent anti-inflammatory agents: In-silico, in-vitro, and in-vivo studiesHala F Rizk, Doha M Beltagy, Seham A Ibrahim, et al.
Bioorganic Chemistry|December 6, 2025
Synthesis, antimicrobial activity and in-silico studies of (1-(1-arylethyl)-1H-1,2,3-triazolyl-2-phenylquinoline-4-carboxylate derivatives with click chemistrySantosh Hande, Abhijit Chavan, Pravin C Mhaske, et al.
Bioorganic Chemistry|December 6, 2025
Development of benztropine-based DAT blockers for Parkinson's disease interventions: A biologic and synthetic overviewEdson D Hernández-Velázquez, Rubén Chávez-Rivera, Rafael Ortíz-Alvarado, et al.
Bioorganic Chemistry|November 15, 2025
Novel 2-oxoethylthio-sulfonamide derivatives targeting pyocyanin/staphyloxanthin producing-pathogens: Antibiofilm, DHPS inhibition and gamma radiation effectsMostafa M Ghorab, Dina S Aboul-Magd, Aiten M Soliman
Bioorganic Chemistry|October 31, 2025
Design, synthesis, and activity evaluation of novel tetrazole-based CYP51 inhibitorsJiachen Zhang, Rui Liu, Yixiang Sun, et al.
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