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Bioorganic Chemistry|August 7, 2025
Discovery of novel selective CYP1B1 inhibitors: Design, synthesis and biological evaluationChuang Li, Ziwei Yi, Weixia Li, et al.
Bioorganic Chemistry|September 13, 2025
Structure-based design of tirabrutinib derivatives as inhibitors of bacterial tryptophanyl-tRNA synthetaseKaijiang Xia, Xiaoying Peng, Lingzhen Xiao, et al.
Bioorganic Chemistry|September 13, 2025
Bis-quaternary ammonium BODIPY derivatives: Photophysical, antimicrobial, and antitumor photodynamic applicationsMingjie Wang, Feng Xiao, Le Mi, et al.
Bioorganic Chemistry|September 10, 2025
Synthesis, Larvicidal Activity, and In Silico Mechanistic Insights of Novel Polyfunctionalized Pyridine Derivatives Against Culex pipiens LMohamed G Abouelenein, Ahmed A El-Rashedy, Doaa R Abdel- Haleem
Bioorganic Chemistry|September 9, 2025
Therapeutic potential, antimicrobial activity against acne-causing bacteria, and modes of action of WKK10 and WRR10, novel cationic antimicrobial peptidesSanti Phosri, Sukanya Tastub, Aekkhaluck Intharuksa, et al.
Bioorganic Chemistry|September 11, 2025
Discovery of natural compounds and their derivatives against neuroinflammation: Pharmacological mechanisms and structure-activity relationshipXianghao Xin, Tieqiang Zong, Zhengyu Hu, et al.
Bioorganic Chemistry|September 10, 2025
Indole-imidazolone derivatives as dual Mcl-1/COX-2 inhibitors: Design-oriented synthesis, molecular docking, and dynamics studies with potential anticancer and anti-inflammatory activitiesPhoebe F Lamie, Peter A Halim, Ahmed M Sayed, et al.
Bioorganic Chemistry|September 8, 2025
Structural hybridization of alepterolic acid with piperazine-benzamide motifs yields potent anticancer agentsXin Wang, Lian Ma, Yanchun Sun, et al.
Bioorganic Chemistry|September 8, 2025
Discovery of Bicyclo[1.1.1]pentane-based Olaparib derivatives as novel PARP inhibitors: A dual-action strategy targeting DNA damage and immune activationBinzhuo Liu, Feng Jin, Fahui Li, et al.
Bioorganic Chemistry|September 8, 2025
Discovery of C-3 nitrothiophene substituted thiochromone derivatives as potent and selective human monoamine oxidase B (hMAO-B) inhibitors for the treatment of atherosclerosisYuqing Lin, Huiming Hu, Xiongwang Li, et al.
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