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Bioorganic Chemistry|January 31, 2026
Identification of quinazolinone and quinoline alkaloids from Peganum harmala L. inducing mitochondria-mediated apoptosis in liver cancerQin Zhang, Jin-Zheng Yu, Chun-Lei Yuan, et al.
Bioorganic Chemistry|February 1, 2026
Structure-activity relationship and anticancer mechanism of febuxostat-1,2,3-triazole hybrids inducing DNA damage and apoptosisXixi Hou, Han Wang, Dong Yan, et al.
Bioorganic Chemistry|January 30, 2026
NIR-triggered synergistic Photothermal therapy and type I photodynamic therapy using supramolecular porphyrin-Phthalocyanine assemblies for the treatment of multidrug-resistant bacterial infectionsWei Su, Jiayin Chen, Chenxiang Lin, et al.
Bioorganic Chemistry|January 22, 2026
Harnessing marine bacteria-derived compounds as anti-quorum sensing agents: a spotlight on sources, mechanisms and emerging technologiesSanthiyagu Prakash, Selvaraj Bharathi, Yolin Angel P A Soundara Rajan, et al.
Bioorganic Chemistry|February 4, 2026
Rational design of 2-substituted thio-7-chloroquinazolin-4(3H)-one derivatives as dual EGFR/VEGFR-2 inhibitors with broad-Spectrum anticancer and apoptotic activitiesMostafa A Mansour, Samar H Abbas, Asmaa M AboulMagd, et al.
Bioorganic Chemistry|January 28, 2026
Small-molecule-based activation of Wnt/β-catenin signaling: An underexplored yet promising strategy for neuroprotectionShakir Ahamad, Parameswari Akshinthala, Faaizah Fazal, et al.
Bioorganic Chemistry|January 30, 2026
Inhibition of the NLRP3 pathway as a strategy for SLE therapyJin Duan, Shuang Yan, Pan Pan, et al.
Bioorganic Chemistry|January 23, 2026
(Z)-4-(substituted benzylidene)-2-phenyl-1H-imidazol-5(4H)-ones are sensitive to tyrosinases of different origins: In vitro and in vivo insightsHee Jin Jung, Hyeon Seo Park, Yeonsoo Jeong, et al.
Bioorganic Chemistry|February 4, 2026
Discovery of mangiferin lipophilic amide derivatives as novel fatty acid synthase inhibitors with potent anti-hepatocellular carcinoma activityYin Li, Liu-Shun Wu, Meng-Ting Lyu, et al.
Bioorganic Chemistry|January 17, 2026
Selectively and efficiently eliciting a ROS-dependent energy crisis within cancer cells through a mitochondria-targeted catechol-based diphenylhextrieneXia-Zhen Bao, Xiao-Rong Ren, Wei Tang, et al.
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