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Bioorganic Chemistry|February 27, 2025
Carbene reactive metabolite explains the hepatotoxicity of the hot flashes drug fezolinetant: A DFT investigationAnila Nuthi, Gauri Mishra, Vaibhav A DixitBioorganic Chemistry|February 26, 2025
Discovery of novel oleanolic acid glycoside derivatives targeting PTP1B/PI3K/AKT signaling pathway for the treatment of breast cancerXiaoping Song, Lina Wang, Yao Liu, et al.Bioorganic Chemistry|February 26, 2025
Discovery of highly potent mTOR inhibitors aimed at suppressing the progression of acute myeloid leukemiaYuanyuan Li, Qiu Han, Qiwen Sun, et al.Bioorganic Chemistry|February 22, 2025
Targeted discovery of diterpene compounds ostamycins with anti-influenza a viral activity from a deepsea-derived Streptomyces strainLukuan Hou, Shuyao Wang, Yuanhang Zhang, et al.Bioorganic Chemistry|February 21, 2025
Design, synthesis, and molecular dynamics-driven evaluation of quinoline-sulfonamide derivatives as potent and selective EGFR inhibitors with promising anti-cancer efficacy and safety profilesMahmoud S Elkotamy, Mohamed K Elgohary, Islam A Elkelesh, et al.Bioorganic Chemistry|February 21, 2025
Novel bis-pocket binding aldose reductase inhibitors sensitize MCF-7/ADR cells to doxorubicin in a dual-role mannerChao Zhang, Shuling Peng, Ziyou Zheng, et al.Bioorganic Chemistry|February 14, 2025
Design, synthesis and biological evaluation of new class of pyrazoles-dihydropyrimidinone derivatives as bone anabolic agentsArvind Kumar Jaiswal, Anuj Raj, Ajay Kishor Kushawaha, et al.Bioorganic Chemistry|February 12, 2025
Design, synthesis and biological evaluation of a novel non-Gemini analog of UVB1 and crystal structure of its complex with the vitamin D receptorUxía Gómez-Bouzó, Carole Peluso-Iltis, Hugo Santalla, et al.Bioorganic Chemistry|January 26, 2025
20-Deoxyingenol ester and ether derivatives: Synthesis, properties and cytotoxicityZijian Liu, Yaxu Wang, Qingning Jiao, et al.Bioorganic Chemistry|January 31, 2025
The insight into the intermolecular interactions between protamine and insulin lisproGuangqi Wang, Qingyu Wang, Hongru Zhu, et al.Pageof 868