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Bioorganic Chemistry|March 9, 2025
Unusual chaetoglobosins and a new type of ferroptosis inducer from an endophytic fungus Chaetomium sp. UJN-EF006Yin-Yin Wang, Yu-Song Wang, Jun-Jiang Li, et al.
Bioorganic Chemistry|March 9, 2025
Unraveling the interaction of pyranocoumarins with P-glycoprotein: Implications for overcoming multidrug resistance in cancer therapyMohamed H Helal, Mosa H Alsehli, Al-Anood M Al-Dies, et al.
Bioorganic Chemistry|March 9, 2025
Polar flagellin glycan heterogeneity of Aeromonas hydrophila strain ATCC 7966TKelly M Fulton, Elena Mendoza-Barberà, Juan M Tomás, et al.
Bioorganic Chemistry|March 6, 2025
Discovery and evaluation of novel Benzohydroxamic acid-indole derivatives as dual inhibitors of ADAM17 and HDAC2 with antitumor activityXiaoxuan Song, Xin Tong, Kaisi Yang, et al.
Bioorganic Chemistry|March 6, 2025
Discovery of bifunctional small molecules targeting PD-L1/VISTA with favorable pharmacokinetics for cancer immunotherapyYao Xiao, Yaru Shi, Chuxiao Shao, et al.
Bioorganic Chemistry|March 23, 2025
A novel MMP-9 inhibitor exhibits selective inhibition in non-small-cell lung cancer harboring EGFR T790M mutation by blocking EGFR/STAT3 signaling pathwayLiangping Li, Minghan Lu, Hui Wang, et al.
Bioorganic Chemistry|March 13, 2025
Discovery of ASGR1 and HMGCR dual-target inhibitors based on supervised learning, molecular docking, molecular dynamics simulations, and biological evaluationYanfeng Liu, Liangying Deng, Feng Ding, et al.
Bioorganic Chemistry|March 13, 2025
Phenylpropanoids of Eleutherococcus senticosus (Rupr. & maxim.) maxim. Alleviate oxidative stress in Alzheimer's disease in vitro and in vivo models by regulating Mst1 and affecting the Nrf2/Sirt3 pathwayRui Yang, Xin Meng, Wei Zhao, et al.
Bioorganic Chemistry|March 13, 2025
Morpholino nicotinamide analogs of ponatinib, dual MNK, p70S6K inhibitors, display efficacy against lung and breast cancersRiddhi Chaudhuri, Neetu Dayal, Joshua Kaiser, et al.
Bioorganic Chemistry|March 19, 2025
Amoebicidal thymol analogues against brain-eating amoeba, Naegleria fowleriMeriam Ben Youssef, Amani Omrani, Ines Sifaoui, et al.
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