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Bioorganic Chemistry|October 12, 2024
Design, synthesis, and biological evaluation of novel 5,7,4'-trimethoxyflavone sulfonamide-based derivatives as highly potent inhibitors of LRPPRC/STAT3/CDK1Rui Wu, Pan Li, Bingbing Hao, et al.
Bioorganic Chemistry|October 12, 2024
Preclinical evaluation of a new technetium-99m labeled neurotensin analogue for NTSR1 targeted radionuclide imagingMostafa Erfani, Azadeh Mikaeili, Zhila Fallah, et al.
Bioorganic Chemistry|October 12, 2024
First dual inhibitors of human topoisomerase IIα and Hsp90 C-terminal domain inhibit the growth of Ewing sarcoma in vitro and in vivoJaka Dernovšek, Dunja Urbančič, Živa Zajec, et al.
Bioorganic Chemistry|September 6, 2024
Discovery of new molecular hybrid derivatives with coumarin scaffold bearing pyrazole/oxadiazole moieties: Molecular docking, POM analyses, in silico pharmacokinetics and in vitro antimicrobial evaluation with identification of potent antitumor pharmacophore sitesGabriela Tataringa, Cristina Tuchilus, Mukhtar Ahmed, et al.
Bioorganic Chemistry|September 7, 2024
Filicinic acid based meroterpenoids from Hypericum elodeoides and their anti-Alzheimer's disease effectsJing-Dian Li, Shou-Lun He, Guang-Hui Wang, et al.
Bioorganic Chemistry|September 6, 2024
Exploring fluorinated heptose phosphate analogues as inhibitors of HldA and HldE, key enzymes in the biosynthesis of lipopolysaccharideJun Cao, José Ignacio Veytia-Bucheli, Lina Liang, et al.
Bioorganic Chemistry|September 8, 2024
Exploring the antifungal potential of novel carbazate derivatives as promising drug candidates against emerging superbug, Candida aurisTazeen Fatima, Zeeshan Fatima, Muriel Billamboz, et al.
Bioorganic Chemistry|September 8, 2024
Development of new LSM-83177 analogues as anti-tumor agents against colorectal cancer targeting p53-MDM2 interactionMohamed K Elgohary, Mahmoud S Elkotamy, Tarfah Al-Warhi, et al.
Bioorganic Chemistry|August 11, 2024
New cyclometalated iridium(III) complexes bearing substituted 2-(1H-benzimidazol-2-yl)quinoline: Synthesis, characterization, electrochemical and anticancer studiesCigdem Sahin, Dogukan Mutlu, Ahmet Erdem, et al.
Bioorganic Chemistry|August 11, 2024
The utility of Streptococcus mutans undecaprenol kinase for the chemoenzymatic synthesis of diverse non-natural isoprenoidsVikas Kumar, Bryce P Johnson, Prashant S Mandal, et al.
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