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Bioorganic Chemistry|January 15, 2026
Targeting the phosphoinositide 3-kinase signaling pathway and epidermal growth factor receptor: The potential of dimethylcardamonin-derived amino acids in triple-negative breast cancer therapyPornthip Chawapun, Nopawit Khamto, Yazdaniyar Fajri Halimi, et al.
Bioorganic Chemistry|January 9, 2026
A thiazole-based hydroxamic acid derivative induces mitochondrial apoptosis and S-phase arrest in MCF-7 cells via DNA minor groove bindingTanima Das, Diya Ghosh, Suvankar Karmakar, et al.
Bioorganic Chemistry|January 8, 2026
Polysaccharides from Scutellaria barbata D. Don: Anti-ulcerative colitis activity evaluation and structure feature analysisShaojie Zhang, Tanggan Wang, Meifeng Li, et al.
Bioorganic Chemistry|January 9, 2026
Screening of novel VEGFR-2-targeting sesquiterpenes from Lindera aggregata and anti-angiogenesis assayWenhui Liu, Haojing Jiang, Caixia Guo, et al.
Bioorganic Chemistry|January 17, 2026
4-Methyl-5-Acetylthiazole (Q11), a novel CYP2E1 inhibitor, has a protective effect on the hepatotoxicity induced by acetaminophenGuang-Xi Yu, Jun Ma, Li-Yang Wang, et al.
Bioorganic Chemistry|January 19, 2026
Mucoadhesive lignin-liposome nanocarriers of coptisine: A multifunctional strategy against antibiotic-resistant Helicobacter pylori biofilmsMohamed Sharaf, Zainab Naser Al-Laith, Tehsin Ullah Khan, et al.
Bioorganic Chemistry|January 11, 2026
Synergistic effects of gentamicin, levofloxacin, and cefotaxime against Aeromonas salmonicida: In vitro and In vivo evaluationXingxiang Wang, Lin Zhong, Bhagyalakshmi Purushothaman, et al.
Bioorganic Chemistry|February 10, 2026
Synthesis of 4-chloro-N'-(2-cyanoacetyl)benzohydrazide derivatives, cytotoxicity, VEGFR-2/EGFRT790M bioassays and in silico docking/ADMET studiesSeham S A Deghaidi, Esraa Nazieh El-Bery, Sabreen Mohamed El-Gamasy, et al.
Bioorganic Chemistry|February 10, 2026
Identification of EEF1A1 as a therapeutic target in TNBC: Anticancer action of a novel Penicillide-derived inhibitor through ribosomal protein regulationJing Yu, Ru-Yi Chen, Yan-Jun Liu, et al.
Bioorganic Chemistry|January 29, 2026
Design, synthesis, and biological evaluation of novel HDAC3 PROTACs for combined therapy with Venetoclax in acute myeloid leukemiaYuxin Chen, Enqiang Liu, Xingchun Ding, et al.
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