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Bioorganic Chemistry|November 28, 2025
Design, synthesis, and anticancer evaluation of spirooxindole-1,2,3-triazole hybrids as potent VEGFR-2 inhibitorsAssem Barakat, Moayad Abdullah Alwehaibi, Abdulmajeed Abdullah Alayyaf, et al.
Bioorganic Chemistry|November 25, 2025
Synthesis and biological evaluation of genipin derivatives as novel xanthine oxidase inhibitors for the anti-hyperuricemia and hepatorenal protection activityHui Sun, Jia-Shu Chen, Bo Zhang, et al.
Bioorganic Chemistry|November 21, 2025
Novel 3-n-butylphthalide derivatives as potent multi-functional anti-IS agents with BBB protective functionLi Shao, Gaofeng Lin, Zhaoxing Chu, et al.
Bioorganic Chemistry|November 23, 2025
Off-target molecular recognition of cyproterone acetate by human lysozyme: conformational remodelling, enzyme modulation, and amyloid inhibitionVanshika, Gulafsha, Kehkashan Naaz, et al.
Bioorganic Chemistry|November 22, 2025
Engineering a fluorescent probe with symmetric D-π-A-π-D configuration for fluorescence discrimination of HSA from BSAHai-Wen Chen, Yi-Ran Zhao, Lu-Yu Li, et al.
Bioorganic Chemistry|November 23, 2025
Novel pyrimidinone scaffolds synthesized via nanotechnology as promising inhibitors of the hepatitis A virus with computational analysesBasant Farag, Islam Ragab, Eman Hassan Elsayed, et al.
Bioorganic Chemistry|November 20, 2025
Neutral-loss scanning-guided discovery of cyanogriamides A-E: β-me-leu-bearing linear lipopeptides exhibiting cytotoxicity via PI3K/Akt/mTOR inhibitionShuai-Shuai Zhang, Ying Wu, Lei Li, et al.
Bioorganic Chemistry|November 20, 2025
Design, synthesis, in vitro and in silico evaluation of thiazole-hydrazone hybrids as potent and safe α-glucosidase inhibitorsAli Ergüç, Emre Kadir Ayan, Muhammed Tilahun Muhammed, et al.
Bioorganic Chemistry|November 20, 2025
Synergistic interplay and dual-target therapeutics: unraveling the coordinated network of SIK2 and PARP-1 in cancer developmentLong-Tian Li, Shi-Chen Zhang, Yue-Ying Yang, et al.
Bioorganic Chemistry|December 10, 2025
Design and synthesis of novel derivatives of bioactive sesquiterpenes Dehydrocostus lactone and Costunolide and their evaluation as leishmanicidal agents with an improved safety profileAnil Bhushan, Diksha Kumari, Bashir Ahmad Lone, et al.
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