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Bioorganic Chemistry|November 17, 2023
Discovery of novel 5-phenylpyrazol receptor interacting protein 1(RIP1) kinase inhibitors as anti-necroptosis agents by combining virtual screening and in vitro and in vivo experimental evaluationsYing Shi, Jiaqin Tang, Shumeng Zhi, et al.
Bioorganic Chemistry|October 27, 2023
Rational design and eco-friendly one-pot multicomponent synthesis of novel ethylidenehydrazineylthiazol-4(5H)-ones as potential apoptotic inducers targeting wild and mutant EGFR-TK in triple negative breast cancerEslam M Abbass, Ahmed A Al-Karmalawy, Marwa Sharaky, et al.
Bioorganic Chemistry|November 3, 2023
Discovery of highly functionalized grayanane diterpenoids from the flowers of Rhododendron molle as potent analgesicsGuijuan Zheng, Lang Huang, Yuanyuan Feng, et al.
Bioorganic Chemistry|November 4, 2023
Brassisterol A, a new ergosterol from co-cultivation of fungi attenuates neuroinflammation via targeting NLRP3/caspase-1/GSDMD pathwayZhou Tong, Luqi Kong, Yuexing Zhang, et al.
Bioorganic Chemistry|November 10, 2023
Identification of novel 3-aryl-1-aminoisoquinolines-based KRASG12C inhibitors: Rational drug design and expedient construction by CH functionalization/annulationZirong Gong, Yu Zhao, Buyi Xu, et al.
Bioorganic Chemistry|October 22, 2023
4-Phenylcoumarin derivatives as new HIV-1 NNRTIs: Design, synthesis, biological activities, and computational studiesRasha Z Batran, Ahmed Sabt, Mohammed A Khedr, et al.
Bioorganic Chemistry|October 8, 2023
Ag/g-C3N4 nanocomposite: Green fabrication and its application as a catalyst in the synthesis of new series of depsipeptides as biologically active compounds and investigation on their anti-breast cancer activityFatemeh Shahi, Fatemeh Kamali, Bahman Sharifzaheh, et al.
Bioorganic Chemistry|October 6, 2023
Prunolactones A-G, proangiogenic isocoumarin derivatives with an unusual 6/6/6/6/6 spiropentacyclic skeleton from the endophytic fungus Phomopsis prunorumXue-Qing Zhang, Zhen-Hong Lu, Guan-Mei Tang, et al.
Bioorganic Chemistry|October 5, 2023
Design, synthesis and biological evaluation of novel 2,4-diaminopyrimidine cinnamyl derivatives as inhibitors of FAK with potent anti-gastric cancer activitiesYang Liu, Li-Jun Kong, Na Li, et al.
Bioorganic Chemistry|October 15, 2023
A bifunctional agent for efficient imaging of PD-L1 and antimelanoma activityJin Wang, Xiaoyan Pan, Ping Hai, et al.
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