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Bioorganic Chemistry|May 28, 2023
Discovery of berberine analogs as potent and highly selective p300/CBP HAT inhibitorsXue Zhong, Huiwen Deng, Min Long, et al.
Bioorganic Chemistry|May 27, 2023
Design, synthesis and biological evaluation of antiparasitic dinitroaniline-ether phospholipid hybridsMarina Roussaki, George E Magoulas, Theano Fotopoulou, et al.
Bioorganic Chemistry|March 4, 2026
Targeting methicillin-susceptible and -resistant Staphylococcus aureus: Design, synthesis, and antibacterial profiling of novel beddomeilactone amidesTashi Palmo, Chetan Paul Singh, Vishwani Jamwal, et al.
Bioorganic Chemistry|March 11, 2026
Discovery of chalcone derivatives as antileishmanial agents: phenotypic screening, exploratory docking and enzymatic assays on trypanothione reductase and related flavoproteinsMargherita Ortalli, Sara Morselli, Tommaso Gritti, et al.
Bioorganic Chemistry|March 11, 2026
Structural characterization of a water-soluble α-D-glucan from Crepis lignea roots and its alleviation of DSS-induced ulcerative colitis in Drosophila melanogasterQian Zhang, Wenyu Wang, Chenhan Wu, et al.
Bioorganic Chemistry|March 12, 2026
Photoenzymatic radical hydrocyanoalkylation for the synthesis of γ-stereogenic nitrilesDong Cui, Chenlu Jin, Dannan Zheng, et al.
Bioorganic Chemistry|February 25, 2026
Structure-guided discovery of 4-phenyl-5-p-tolyloxymethyl-4H-1,2,4-triazole thioethers as 15-lipoxygenase inhibitors using integrated in vitro, structure-activity relationship, in silico, cytotoxicity towards MCF-7 cell line, DNA docking and MD simulation methodsDeeba Nawaz, Bushra Bashir, Ambar Iqbal, et al.
Bioorganic Chemistry|February 25, 2026
Design, synthesis and biological evaluation of novel fluoroquinolone-uracil hybrids against methicillin-resistant Staphylococcus Epidermidis (MRSE) infectionsHuan Du, Qiong Yang, Le Li, et al.
Bioorganic Chemistry|March 14, 2026
Design and synthesis of benzimidazole-based derivatives with antimicrobial activity: mechanistic insights into ROS-mediated oxidative damage, hemolytic assessment, and molecular docking studiesMohamed A Omar, Ahmed Temirak, Mohamed Abdelraof, et al.
Bioorganic Chemistry|February 19, 2026
Repurposing amide-based drugs unveils inhibition mechanisms of plasmodium falciparum Plasmepsin V enzymatic activity for antimalarial therapyAnitadevi K Prajapati, Garima Singh, Manu Lopus, et al.
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