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Bioorganic Chemistry|May 31, 2026
Discovery of pyridine amide derivatives exhibiting vasodilatory activityYa-Lan Wang, Hui Liu, Wen-Zhe Nie, et al.
Bioorganic Chemistry|May 31, 2026
NH2-trimethyl lock (NH2-TML): a stable and effective adapter for exatecan-based antibody-drug conjugatesXuzhuo Li, Lizhe Bai, Xiaomei Li, et al.
Bioorganic Chemistry|May 27, 2026
Structure-selective binding and bioactivity of chlorine-substituted cyanine dyes with DNA, RNA, and lipid membranesNina Vukadinović, Ivo Crnolatac, Atanas Kurutos, et al.
Bioorganic Chemistry|May 27, 2026
Glycine-zipper-derived synthetic amino acid-containing peptides as amyloid-β aggregation inhibitors: structural and mechanistic investigationsRajesh Parmar, Naina Sehra, Indresh K Maurya, et al.
Bioorganic Chemistry|May 27, 2026
Antineoplastic multi-targeted spiro[indoline-3,2'-pyrrolidines] incorporating urea function: Rational design, synthesis and bio-properties studiesNehmedo G Fawzy, Siva S Panda, Mohamed S Bekheit, et al.
Bioorganic Chemistry|June 1, 2026
Rational design and synthesis of a heterocycle scaffold for DNMT3A inhibitionTing Chen, Ahmad Elbahnsi, Elodie Olivier, et al.
Bioorganic Chemistry|May 30, 2026
Rationally designed quinazolinone derivatives incorporating acetyl pyridine and thiazole scaffolds as dual EGFR/HER-2 anticancer agents: integrated biological evaluation, molecular profiling, and advanced computational studiesHagar S El-Hema, Rasha A-S El-Ghorab, Mohamed A Hawata, et al.
Bioorganic Chemistry|June 5, 2026
From rational design to mechanistic insight: A benzamide-based FtsZ inhibitor as a novel antibacterial agent against Xanthomonas oryzae pv. oryzaeJiahao Wang, Ping Chen, Yu Li, et al.
Bioorganic Chemistry|June 5, 2026
Synthesis and multi-target biological evaluation of Schiff base metal complexes: tuning anticancer efficacy and enzyme inhibition via metal center variationAnmol Singh, Anamika Singh, Dhiraj Raj, et al.
Bioorganic Chemistry|June 5, 2026
Beyond PARP-HDAC inhibition: mechanistic rationale and medicinal chemistry insights from single to shared-target strategiesEman M Elkafoury, Shahenda Mahmoud, Kamyar Afarinkia, et al.
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