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Bioorganic Chemistry|July 2, 2026
Assessing the cytotoxic effects of group IX metal N-heterocyclic carbene complexes of iridium and rhodium on B16-F10 melanoma and non-cancerous RAW 264.7 cellsEstefan van Vuuren, Carolyn C Nadasen, Frederick P Malan, et al.
Bioorganic Chemistry|July 2, 2026
Integrative multi-omics and machine learning reveal PLAUR as a Pan-Cancer prognostic biomarker and potential therapeutic targetJin Li, Yaxian Luo, Shuangyang Li, et al.
Bioorganic Chemistry|July 2, 2026
Synthesis and biological evaluation of 6,9-disubstituted purine analogues inducing autophagy-mediated apoptosis and potentiating carboplatin response in high-grade serous ovarian cancerPınar Kul Karadenizli, Deren Demirel Yavuz, Duygu Altıparmak, et al.
Bioorganic Chemistry|June 29, 2026
Rational design and synthesis of pyrazole-based sulfonamides as dual carbonic anhydrase and PRAK-targeting anticancer agentsMariam M Fakhry, Mohamed A Said, Noha Zeidan, et al.
Bioorganic Chemistry|June 18, 2026
Millepurpan from Astragali Radix binds condensin SMC2 to reverse microglial cell cycle arrest and metabolic reprogramming in neuroinflammationYue Li, Xue-Fei Yang, Shui-Yuan Yang, et al.
Bioorganic Chemistry|June 19, 2026
Discovery of new thiazolyl hydrazone derivatives as anti-breast cancer agents: Synthesis, biological evaluation and in silico studiesFatih Tok, Hilal Kabadayı Ensarioğlu, Faika Başoğlu, et al.
Bioorganic Chemistry|July 8, 2026
Synthesis of compounds including isoxazoline and pyrazoline units derivatives from norbornadiene and their antibacterial and anti-quorum sensing propertiesYadigar Adiloglu, Nurcan Erbil, Ali Yavari, et al.
Bioorganic Chemistry|July 8, 2026
Design, synthesis, biological evaluation, DFT and molecular docking studies of novel isoxazolines containing cyclic amideXiangwei Liu, Guozhu Sheng, Ben-Yang Ji, et al.
Bioorganic Chemistry|July 7, 2026
Discovery and biological evaluation of novel TLR2 antagonists through structure-based virtual screening and molecular dynamics simulationsPeng Jiao, Haonian Jin, Chaochun Wei, et al.
Bioorganic Chemistry|July 7, 2026
Design and discovery of a novel interleukin-11 derived peptide with antagonistic activity for the treatment of renal fibrosisNingning Pang, Jian Li, Xing Cheng, et al.
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