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Bioorganic Chemistry|August 25, 2026
Short chain length polyhydroxyalkanoate (scl-PHA) produced by the marine bacterium Pseudomonas sputi MaRe06 inhibits Staphylococcus aureus biofilm formationLeidy J García Maza, Deisiane Da Rosa, Walter O Beys-da-Silva, et al.
Bioorganic Chemistry|September 3, 2026
A light-gated "membrane-to-mitochondria" sequentially targeted AIE photosensitizer for potentiated photodynamic therapy and imaging of breast cancerTonghui Huang, Fangzhu Huang, Nian Shi, et al.
Bioorganic Chemistry|September 8, 2026
Discovery of a new class based on 6-methoxypyrimidine as efficient low weight reversible inhibitors of SARS-CoV-2 main protease (Mpro) with antiviral activityIsadora Serraglio Fortes, Marcela Silva Lopes, Thais Helena Maciel Fernandes, et al.
Bioorganic Chemistry|August 31, 2026
Structure-based optimization, in vitro profiling, and ADMET prediction of Celastrol derivatives as potent prolyl endopeptidase inhibitorsTian-Ge Wang, Jing Zhang, Chang Dai, et al.
Bioorganic Chemistry|August 31, 2026
Design, synthesis, and structural characterization of covalent tetrahydroquinoline-based inhibitors of coronavirus 3CLproAnastasia A Pronina, Dmitriy N Shcherbakov, Artem P Sanchez-Pimentel, et al.
Bioorganic Chemistry|August 31, 2026
Benzylisoquinoline Alkaloids from NelumbinisPlumula as Potential Butyrylcholinesterase Inhibitors: Isolation, Characterization and Bioactivity EvaluationWenjun Wei, Dongge Wang, Jigao Yang, et al.
Bioorganic Chemistry|September 2, 2026
A hydrogen peroxide-responsive near-infrared fluorescent probe for visualizing redox-associated signals in acute colitis and gastrointestinal tumor models and monitoring treatment-related changesSi-Yan Yu, Yu-Han Pu, Peng-Wei Zhu
Bioorganic Chemistry|September 1, 2026
Synthesis, multi-target enzyme inhibition, and in silico evaluation of phthalimide derivatives with relevance to tuberculosis-associated pathophysiologyAneela Khushal, Sara Khan, Umar Farooq, et al.
Bioorganic Chemistry|August 27, 2026
Synthesis, structural characterization and antifungal activity of azo-based compounds bearing hydroxy and nitro terminal groupsNurul Asma Razali, Zuhair Jamain, Fauze Mahmud, et al.
Bioorganic Chemistry|September 15, 2026
Design, synthesis, and biological evaluation of non-conjugated Biaryl amide URAT1 inhibitors as potent Uricosuric agentsWei Liu, Shuhan Sun, Yanhong Liu, et al.
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