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Briefings in Bioinformatics|February 3, 2026
scGACL: a generative adversarial network with multi-scale contrastive learning for accurate single-cell RNA sequencing imputationYanlin Jiang, Mengyuan Zhao, Jiahui Yan, et al.Briefings in Bioinformatics|January 28, 2026
BiGvCL: bipartite graph-based cross-domain contrastive learning model for the predicting drug-gene interactionsShida He, Zixu Wang, Jing Li, et al.Briefings in Bioinformatics|February 5, 2026
Systematic evaluation of computational tools to predict the effects of mutations on protein-ligand binding affinity in the absence of experimental structuresQisheng Pan, Stephanie Portelli, Thanh Binh Nguyen, et al.Briefings in Bioinformatics|February 3, 2026
PGVDA: a pathway-aggregated genetic dosage framework for interpretable disease classification using machine learningSanghyun Shon, Younhee Ko, Hojin Yoon, et al.Briefings in Bioinformatics|January 29, 2026
Multi-platform integration of brain and CSF proteomes reveals biomarker panels for Alzheimer's diseaseWei-Yun Tsai, Pieter Giesbertz, Stephan Breimann, et al.Briefings in Bioinformatics|August 3, 2025
Dual balanced augmented topological noncoding RNA disease triplet association in heterogeneous graphsLaiyi Fu, Yangyi Zhou, Hongqiang Lyu, et al.Briefings in Bioinformatics|June 29, 2025
TransMA: an explainable multi-modal deep learning model for predicting properties of ionizable lipid nanoparticles in mRNA deliveryKun Wu, Zixu Wang, Xiulong Yang, et al.Briefings in Bioinformatics|June 29, 2025
cfMethylPre: deep transfer learning enhances cancer detection based on circulating cell-free DNA methylation profilingXuchao Zhang, Jing Chen, Yongtian Wang, et al.Briefings in Bioinformatics|June 14, 2025
ProtPhage: a deep learning framework for phage viral protein identification and functional annotationYuehua Ou, Qiyi Chen, Ningyu Zhong, et al.Briefings in Bioinformatics|June 14, 2025
scValue: value-based subsampling of large-scale single-cell transcriptomic data for machine and deep learning tasksLi Huang, Weikang Gong, Dongsheng ChenPageof 544