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Briefings in Bioinformatics|August 10, 2026
G2DR: a genotype-first framework for genetics-informed target prioritization and drug repurposingMuhammad Muneeb, David B Ascher
Briefings in Bioinformatics|July 17, 2026
Histopathology-centered computational evolution of spatial omics: integration, mapping, and foundation modelsNinghui Hao, Xinxing Yang, Boshen Yan, et al.
Briefings in Bioinformatics|August 12, 2026
A systematic benchmarking framework and dual-view optimization strategy for single-cell DNA methylation imputationHaitian Liang, Heyang Hua, Siyu Li, et al.
Briefings in Bioinformatics|August 12, 2026
SCONE: a subset-contrastive method for multi-omics network embeddingPedro Henrique da Costa Avelar, Jonathan Cardoso-Silva, Min Wu, et al.
Briefings in Bioinformatics|September 7, 2026
Interpretable deep neural network identifies robust biomarkers for diseases with mechanistic insights from omics dataXiaoyue Hu, Yuhao Ma, Ruixing Ming, et al.
Briefings in Bioinformatics|September 8, 2026
DPAS-Graph: adaptive spatial-feature relation learning for spatial RNA-to-protein prediction and virtual protein profilingMingyuan Xu, Zhixin Dong, Bisheng Xia
Briefings in Bioinformatics|September 10, 2026
ELISA (Embedding-Linked Interactive Single-cell Agent): an interpretable hybrid generative Artificial Intelligence agent for expression-grounded discovery in single-cell genomicsOmar Coser
Briefings in Bioinformatics|September 10, 2026
Somatic likelihood tiering: an interpretable post-calling triage protocol for tumor-only whole-exome variant reviewKonrad Stawiski, Sophia C Kamran, Júlia Perera-Bel, et al.
Briefings in Bioinformatics|September 9, 2026
lagCI enables inference of temporal causal relationships from dense multi-omic time seriesYifei Ge, Shunpeng Bai, Zirui Qiang, et al.
Briefings in Bioinformatics|September 11, 2026
scASprofiler: profiling single-cell RNA splicing with a deep convolutional generative networkPengwei Hu, Pengcheng Song, Bingjie Dai, et al.
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