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CPT: Pharmacometrics & Systems Pharmacology|September 1, 2022
An exposure-response analysis of ponesimod clinical efficacy in a randomized phase III study in patients with relapsing multiple sclerosisBelén Valenzuela, Per Olsson Gisleskog, Italo Poggesi, et al.CPT: Pharmacometrics & Systems Pharmacology|December 10, 2021
Stable warfarin dose prediction in sub-Saharan African patients: A machine-learning approach and external validation of a clinical dose-initiation algorithmInnocent G Asiimwe, Marc Blockman, Karen Cohen, et al.CPT: Pharmacometrics & Systems Pharmacology|July 22, 2016
Multiscale Systems-Pharmacology Pipeline to Assess the Prophylactic Efficacy of NRTIs Against HIV-1S Duwal, V Sunkara, M von KleistCPT: Pharmacometrics & Systems Pharmacology|July 21, 2016
Towards a Best Practice Approach in PBPK Modeling: Case Example of Developing a Unified Efavirenz Model Accounting for Induction of CYPs 3A4 and 2B6A Ke, Z Barter, K Rowland-Yeo, et al.CPT: Pharmacometrics & Systems Pharmacology|June 17, 2020
Data Digitizing: Accurate and Precise Data Extraction for Quantitative Systems Pharmacology and Physiologically-Based Pharmacokinetic ModelingJan-Georg Wojtyniak, Hannah Britz, Dominik Selzer, et al.CPT: Pharmacometrics & Systems Pharmacology|June 17, 2020
A Physiologically-Based Quantitative Systems Pharmacology Model of the Incretin Hormones GLP-1 and GIP and the DPP4 Inhibitor SitagliptinPavel Balazki, Stephan Schaller, Thomas Eissing, et al.CPT: Pharmacometrics & Systems Pharmacology|May 27, 2020
Population Pharmacodynamic Model of Neutrophil Margination and Tolerance to Describe Effect of Sarilumab on Absolute Neutrophil Count in Patients with Rheumatoid ArthritisPavel Kovalenko, Anne Paccaly, Anita Boyapati, et al.CPT: Pharmacometrics & Systems Pharmacology|May 27, 2020
Importance of Stability Analysis When Using Nonlinear Semimechanistic Models to Describe Drug-Induced HematotoxicityChiara Fornari, Carmen Pin, James W T Yates, et al.CPT: Pharmacometrics & Systems Pharmacology|August 10, 2022
Cluster Gauss-Newton method analyses of PBPK model parameter combinations of coproporphyrin-I based on OATP1B-mediated rifampicin interaction studiesTakashi Yoshikado, Yasunori Aoki, Tatsuki Mochizuki, et al.CPT: Pharmacometrics & Systems Pharmacology|May 5, 2021
Detecting placebo and drug effects on Parkinson's disease symptoms by longitudinal item-score modelsChao Chen, Siv Jönsson, Shuying Yang, et al.Pageof 152