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CPT: Pharmacometrics & Systems Pharmacology|January 19, 2026
Validating Physiologically-Based Pharmacokinetic Models Using the Continuous Ranked Probability Score: Beyond Being Correct on AverageLaurens Sluijterman, Marjolein van Borselen, Rick Greupink, et al.
CPT: Pharmacometrics & Systems Pharmacology|January 20, 2026
Evaluating the Impact of Intestinal Bile Salts on Drug Absorption Using PBPK Modeling: Case Studies With Efavirenz, Cinnarizine, and PosaconazoleLaura G Al-Amiry Santos, Sebastian Polak, Karen Rowland Yeo
CPT: Pharmacometrics & Systems Pharmacology|January 16, 2026
Albumin Levels Are Predictive of Cachexia-Induced Time-Dependent Clearance of Therapeutic Antibodies: A Physiologically Based Pharmacokinetic Model of DurvalumabJeffrey R Proctor, Harvey Wong
CPT: Pharmacometrics & Systems Pharmacology|January 16, 2026
Brain Amyloid Plaque Levels Affect Clinical Progression in Alzheimer Disease: Assessment of Amyloid PET and Change in CDR-SB Utilizing Semi-Mechanistic ModelPratik Bhagunde, Natasha Penner, Brian A Willis, et al.
CPT: Pharmacometrics & Systems Pharmacology|January 16, 2026
Integrating Population Approaches With Physiologically Based Pharmacokinetic Models: A Novel Framework for Parameter EstimationDonato Teutonico, David Marchionni, Marc Lavielle, et al.
CPT: Pharmacometrics & Systems Pharmacology|March 13, 2023
A mechanistic modeling platform of SGLT2 inhibition: Implications for type 1 diabetesVictor Sokolov, Tatiana Yakovleva, Leonid Stolbov, et al.
CPT: Pharmacometrics & Systems Pharmacology|February 15, 2023
Population pharmacokinetic modeling and simulation of maribavir to support dose selection and regulatory approval in adolescents with posttransplant refractory cytomegalovirusKefeng Sun, Siobhan Hayes, Colm Farrell, et al.
CPT: Pharmacometrics & Systems Pharmacology|February 16, 2023
Model-based prediction of effective target exposure for MEN1611 in combination with trastuzumab in HER2-positive advanced or metastatic breast cancer patientsElena M Tosca, Elisa Borella, Chiara Piana, et al.
CPT: Pharmacometrics & Systems Pharmacology|February 16, 2023
Characterizing the exposure-response relationship of idecabtagene vicleucel in patients with relapsed/refractory multiple myelomaJamie N Connarn, Han Witjes, Marielle van Zutphen-van Geffen, et al.
CPT: Pharmacometrics & Systems Pharmacology|February 14, 2023
A prognostic baseline blood biomarker and tumor growth kinetics integrated model in paclitaxel/platinum treated advanced non-small cell lung cancer patientsFrancis Williams Ojara, Andrea Henrich, Nicolas Frances, et al.
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