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CPT: Pharmacometrics & Systems Pharmacology|March 16, 2017
Investigating Transporter-Mediated Drug-Drug Interactions Using a Physiologically Based Pharmacokinetic Model of RosuvastatinQ Wang, M Zheng, T Leil
CPT: Pharmacometrics & Systems Pharmacology|April 4, 2025
SpatialCNS-PBPK: An R/Shiny Web-Based Application for Physiologically Based Pharmacokinetic Modeling of Spatial Pharmacokinetics in the Human Central Nervous System and Brain TumorsCharuka D Wickramasinghe, Seongho Kim, Jing Li
CPT: Pharmacometrics & Systems Pharmacology|April 23, 2025
Development of a Heuristic Machine Analogy Method for Model Simplification With an Application to a Large-Scale Model of Gi/Gs SignalingLiang Yang, David Finlay, Michelle Glass, et al.
CPT: Pharmacometrics & Systems Pharmacology|April 18, 2025
Model-Based Meta-Analysis of the Relationship Between Pioglitazone and Histological Outcomes in Metabolic Dysfunction-Associated Steatohepatitis PatientsQuyen Thi Tran, Tham Thi Bui, Lien Thi Ngo, et al.
CPT: Pharmacometrics & Systems Pharmacology|May 2, 2025
A Novel Empirical Autoinduction Model to Characterize the Population Pharmacokinetics and Recommend Dose for Repotrectinib in Adult and Adolescents With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 RearrangementsShengnan Du, Zheyi Hu, Jun Shen, et al.
CPT: Pharmacometrics & Systems Pharmacology|March 31, 2025
Middle-Out Physiologically Based Pharmacokinetic Modeling to Support Pediatric Dosing Recommendation for AlectinibTamara van Donge, Elena Guerini, Amaury O'Jeanson, et al.
CPT: Pharmacometrics & Systems Pharmacology|June 17, 2025
Development and Verification of a Physiologically Based Pharmacokinetic Model of Furmonertinib and Its Main Metabolite for Drug-Drug Interaction PredictionsYali Wu, Helena Leonie Hanae Loer, Yifan Zhang, et al.
CPT: Pharmacometrics & Systems Pharmacology|May 27, 2025
Target-Mediated Drug Disposition (TMDD) Revisited: High Versus Low-Affinity Approximations of the TMDD ModelRonny Straube
CPT: Pharmacometrics & Systems Pharmacology|May 12, 2025
Comprehensive Safety Exposure-Response Analysis to Support Ritlecitinib Dose SelectionYeamin Huh, Ruolun Qiu, John Prybylski, et al.
CPT: Pharmacometrics & Systems Pharmacology|August 22, 2025
A Combined Modeling Approach to Predict the Effect of Gastric Emptying Delay on the Pharmacokinetics of Small MoleculesMaria M Posada, Karen B Schneck, Bridget L Morse, et al.
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