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CPT: Pharmacometrics & Systems Pharmacology|May 15, 2023
Sabatolimab (MBG453) model-informed drug development for dose selection in patients with myelodysplastic syndrome/acute myeloid leukemia and solid tumorsSiyan Xu, Na Zhang, Mikael L Rinne, et al.CPT: Pharmacometrics & Systems Pharmacology|May 24, 2023
Population pharmacokinetic analysis of sparsentan in healthy volunteers and patients with focal segmental glomerulosclerosisRussell Wada, Huub Jan Kleijn, Lu Zhang, et al.CPT: Pharmacometrics & Systems Pharmacology|July 4, 2020
QSP-IO: A Quantitative Systems Pharmacology Toolbox for Mechanistic Multiscale Modeling for Immuno-Oncology ApplicationsRichard J Sové, Mohammad Jafarnejad, Chen Zhao, et al.CPT: Pharmacometrics & Systems Pharmacology|January 24, 2014
Identifying druggable targets by protein microenvironments matching: application to transcription factorsT Liu, R B AltmanCPT: Pharmacometrics & Systems Pharmacology|May 16, 2014
Integrated systems pharmacology analysis of clinical drug-induced peripheral neuropathyJ Hur, A Y Guo, W Y Loh, et al.CPT: Pharmacometrics & Systems Pharmacology|August 21, 2022
Performance of Cox proportional hazard models on recovering the ground truth of confounded exposure-response relationships for large-molecule oncology drugsVictor Poon, Dan LuCPT: Pharmacometrics & Systems Pharmacology|November 9, 2022
Disease trajectory of SLE clinical endpoints and covariates affecting disease severity and probability of response: Analysis of pooled patient-level placebo (Standard-of-Care) data to enable model-informed drug developmentKosalaram Goteti, Jonathan French, Ramon Garcia, et al.CPT: Pharmacometrics & Systems Pharmacology|May 6, 2021
Population pharmacokinetic modeling of molibresib and its active metabolites in patients with solid tumors: A semimechanistic autoinduction modelAnu Shilpa Krishnatry, Alexander Voelkner, Arindam Dhar, et al.CPT: Pharmacometrics & Systems Pharmacology|June 20, 2020
Timing of Antiviral Treatment Initiation is Critical to Reduce SARS-CoV-2 Viral LoadAntonio Gonçalves, Julie Bertrand, Ruian Ke, et al.CPT: Pharmacometrics & Systems Pharmacology|August 25, 2022
A multi-model approach to predict efficacious clinical dose for an anti-TGF-β antibody (GC2008) in the treatment of osteogenesis imperfectaPanteleimon D Mavroudis, Nikhil Pillai, Qingping Wang, et al.Pageof 153