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CPT: Pharmacometrics & Systems Pharmacology|July 4, 2025
Prediction of a CLDN18.2 Targeted Antibody Drug Conjugate Pharmacokinetics in Cancer Patients Using PBPK Modeling and SimulationChiara Zunino, Sichen Wang, Yanyan Zhang, et al.
CPT: Pharmacometrics & Systems Pharmacology|July 4, 2025
Pirana and Integrated PMX Tools, a Workbench for NONMEM, NLME, pyDarwin, and RsNLMERong Chen, Mark Sale, James Craig, et al.
CPT: Pharmacometrics & Systems Pharmacology|July 27, 2025
Predicting Residual 21-Hydroxylase Enzymatic Activity in Pediatric and Adult Congenital Adrenal Hyperplasia Patients: Towards Individualized TherapyDavide Bindellini, Robin Michelet, Yersultan Mirasbekov, et al.
CPT: Pharmacometrics & Systems Pharmacology|June 25, 2025
Evaluation of the Drug-Drug Interaction Potential of the GlyT1 Inhibitor Iclepertin (BI 425809): A Physiologically Based Pharmacokinetic (PBPK) Modeling ApproachElin M Matsson, Michael Desch, Valerie Nock, et al.
CPT: Pharmacometrics & Systems Pharmacology|June 26, 2025
Incorporating Multiple Imputation Into Tanezumab Dose-Response Modeling of WOMAC Pain CFB Across Six Randomized Placebo-Controlled Phase 3 TrialsMartin Boucher, Scott Marshall, Puneet Gaitonde
CPT: Pharmacometrics & Systems Pharmacology|July 16, 2025
From In Vitro Efficacy to Long-Term HbA1c Response for GLP-1R/GlucagonR Agonism Using the 4GI-HbA1c Systems ModelRolien Bosch, Marcella Petrone, Rosalin Arends, et al.
CPT: Pharmacometrics & Systems Pharmacology|December 14, 2025
A Quantitative Systems Pharmacology (QSP) Model of Acute Hepatitis B Virus Infection: Mechanistic Insights and Foundations for Future ExtensionsClémence Boivin-Champeaux, Stephan Schmidt, Scott Balsitis, et al.
CPT: Pharmacometrics & Systems Pharmacology|December 15, 2025
A Systematic Review and Model-Based Meta-Analysis of Pegylated-Interferon-α-Induced HBsAg Loss in Chronic Hepatitis B Virus InfectionNathan J Hanan, Matthew L Zierhut, Ahmed Nader, et al.
CPT: Pharmacometrics & Systems Pharmacology|December 11, 2025
Talazoparib Formulation Bridging in Cancer Patients-Challenges and the Critical Role of Model-Informed Drug Development in Approval Despite Failed BioequivalenceDiane Wang, Cathy Cen Guo, Xizhe Gao, et al.
CPT: Pharmacometrics & Systems Pharmacology|December 4, 2025
Analyzing Pharmacodynamic Count Data That Rapidly Decrease to ZeroWalter M Yamada, Alan Schumitzky, Alona Kryshchenko, et al.
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