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CPT: Pharmacometrics & Systems Pharmacology|April 16, 2024
Population pharmacokinetics and exposure-response analyses of polatuzumab vedotin in patients with previously untreated DLBCL from the POLARIX studyRong Deng, Leonid Gibiansky, Tong Lu, et al.
CPT: Pharmacometrics & Systems Pharmacology|March 27, 2024
Quantitative evaluation of trastuzumab deruxtecan pharmacokinetics and pharmacodynamics in mouse models of varying degrees of HER2 expressionChristina Vasalou, Theresa A Proia, Laura Kazlauskas, et al.
CPT: Pharmacometrics & Systems Pharmacology|September 13, 2023
Model-based assessment of neutrophil-mediated phagocytosis and digestion of bacteria across in vitro and in vivo studiesAnders Thorsted, Anh Duc Pham, Lena E Friberg, et al.
CPT: Pharmacometrics & Systems Pharmacology|September 16, 2023
Mechanistic modeling projections of antibody persistence after homologous booster regimens of COVID-19 vaccine Ad26.COV2.S in humansAnna Dari, Philippe Jacqmin, Yuki Iwaki, et al.
CPT: Pharmacometrics & Systems Pharmacology|August 25, 2023
A dynamic model of the intestinal epithelium integrates multiple sources of preclinical data and enables clinical translation of drug-induced toxicityLouis Gall, Ferran Jardi, Lieve Lammens, et al.
CPT: Pharmacometrics & Systems Pharmacology|September 7, 2023
Optimized infusion rates for N,N-dimethyltryptamine to achieve a target psychedelic intensity based on a modeling and simulation frameworkEmma Eckernäs, Jeroen Koomen, Christopher Timmermann, et al.
CPT: Pharmacometrics & Systems Pharmacology|January 2, 2024
Clofazimine pharmacokinetics in HIV-infected adults with diarrhea: Implications of diarrheal disease on absorption of orally administered therapeuticsCindy X Zhang, Thomas M Conrad, David Hermann, et al.
CPT: Pharmacometrics & Systems Pharmacology|December 15, 2023
Deep compartment models: A deep learning approach for the reliable prediction of time-series data in pharmacokinetic modelingAlexander Janssen, Frank W G Leebeek, Marjon H Cnossen, et al.
CPT: Pharmacometrics & Systems Pharmacology|December 18, 2023
Development and application of neonatal physiology-based pharmacokinetic models of amikacin and fosfomycin to assess pharmacodynamic target attainmentChristopher A Darlow, Neil Parrott, Richard W Peck, et al.
CPT: Pharmacometrics & Systems Pharmacology|December 13, 2023
Tumor growth inhibition modeling in patients with second line biliary tract cancer and first line non-small cell lung cancer based on bintrafusp alfa trialsAna-Marija Milenković-Grišić, Nadia Terranova, Diane R Mould, et al.
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