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CPT: Pharmacometrics & Systems Pharmacology|June 4, 2021
A population pharmacokinetic-pharmacodynamic model of YH12852, a highly selective 5-hydroxytryptamine 4 receptor agonist, in healthy subjects and patients with functional constipationSiun Kim, Hyun A Lee, Seong Bok Jang, et al.CPT: Pharmacometrics & Systems Pharmacology|June 4, 2021
Pharmacometric analysis linking immunoglobulin exposure to clinical efficacy outcomes in chronic inflammatory demyelinating polyneuropathyMichael A Tortorici, Theresa Yuraszeck, David Cornblath, et al.CPT: Pharmacometrics & Systems Pharmacology|November 17, 2020
A Personalized Medicine Approach Using Clinical Utility Index and Exposure-Response Modeling Informed by Patient Preferences DataInsa Winzenborg, Ahmed M Soliman, Mohamad ShebleyCPT: Pharmacometrics & Systems Pharmacology|June 1, 2021
Population pharmacokinetics and exposure-response analyses of varenicline in adolescent smokersDaryl J Fediuk, Kevin Sweeney, Vaishali Sahasrabudhe, et al.CPT: Pharmacometrics & Systems Pharmacology|March 10, 2020
Model-Informed Drug Development for Everolimus Dosing Selection in Pediatric Infant PatientsFrancois Pierre Combes, Heidi J Einolf, Neva Coello, et al.CPT: Pharmacometrics & Systems Pharmacology|June 5, 2014
Exposure-response modeling of clinical end points using latent variable indirect response modelsC HuCPT: Pharmacometrics & Systems Pharmacology|May 11, 2023
A multistate modeling and simulation framework to learn dose-response of oncology drugs: Application to bintrafusp alfa in non-small cell lung cancerHan Liu, Ana-Marija Milenković-Grišić, Sreenath M Krishnan, et al.CPT: Pharmacometrics & Systems Pharmacology|May 11, 2023
Physiologically-based pharmacokinetic modeling of quinidine to establish a CYP3A4, P-gp, and CYP2D6 drug-drug-gene interaction networkDenise Feick, Simeon Rüdesheim, Fatima Zahra Marok, et al.CPT: Pharmacometrics & Systems Pharmacology|January 10, 2014
A multiscale model of interleukin-6-mediated immune regulation in Crohn's disease and its application in drug discovery and developmentG Dwivedi, L Fitz, M Hegen, et al.CPT: Pharmacometrics & Systems Pharmacology|January 10, 2014
Scale reduction of a systems coagulation model with an application to modeling pharmacokinetic-pharmacodynamic dataA Gulati, G K Isbister, S B DuffullPageof 153