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Cancer Discovery|October 14, 2025
Glucocorticoids Unleash Immune-dependent Melanoma Control through Inhibition of the GARP/TGF β AxisCharles H Earnshaw, Poppy Dunn, Shih-Chieh Chiang, et al.Cancer Discovery|March 28, 2025
Somatic uniparental disomy of PTEN in endothelial cells causes vascular malformations in patients with PTEN Hamartoma Tumor SyndromeSandra D Castillo, Xabier Perosanz, Andrew K Ressler, et al.Cancer Discovery|July 23, 2014
Rare mutations in RINT1 predispose carriers to breast and Lynch syndrome-spectrum cancersDaniel J Park, Kayoko Tao, Florence Le Calvez-Kelm, et al.Cancer Discovery|August 2, 2014
Cell-cycle reprogramming for PI3K inhibition overrides a relapse-specific C481S BTK mutation revealed by longitudinal functional genomics in mantle cell lymphomaDavid Chiron, Maurizio Di Liberto, Peter Martin, et al.Cancer Discovery|December 5, 2013
Epithelial-to-mesenchymal transition rewires the molecular path to PI3K-dependent proliferationMegan B Salt, Sourav Bandyopadhyay, Frank McCormickCancer Discovery|August 6, 2014
Greater than the sum of its parts: single-nucleus sequencing identifies convergent evolution of independent EGFR mutants in GBMBeatrice Gini, Paul S MischelCancer Discovery|August 9, 2014
Discovery of biomarkers predictive of GSI response in triple-negative breast cancer and adenoid cystic carcinomaAlexander Stoeck, Serguei Lejnine, Andrew Truong, et al.Cancer Discovery|May 10, 2013
Two is better than one: combining IGF1R and MEK blockade as a promising novel treatment strategy against KRAS-mutant lung cancerRon Chen, E Alejandro Sweet-CorderoCancer Discovery|April 26, 2013
Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitorsErick J Morris, Sharda Jha, Clifford R Restaino, et al.Cancer Discovery|April 3, 2013
GSK-3α promotes oncogenic KRAS function in pancreatic cancer via TAK1-TAB stabilization and regulation of noncanonical NF-κBDeepali Bang, Willie Wilson, Meagan Ryan, et al.Pageof 428