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Cell Chemical Biology|May 16, 2025
Engineering ERα degraders with pleiotropic ubiquitin ligase ligands maximizes therapeutic efficacy by co-opting distinct effector ligasesAnna Shemorry, Willem den Besten, Melinda M Mulvihill, et al.Cell Chemical Biology|May 16, 2025
Pantothenate kinase is an effective target for antifungal therapyJessica Regan, Christian DeJarnette, Parker Reitler, et al.Cell Chemical Biology|April 18, 2025
CDK2 heterobifunctional degraders co-degrade CDK2 and cyclin E resulting in efficacy in CCNE1-amplified and overexpressed cancersNicholas Kwiatkowski, Tong Liang, Zhe Sha, et al.Cell Chemical Biology|April 1, 2025
Understanding, inhibiting, and engineering membrane transporters with high-throughput mutational screensSilas T Miller, Christian B Macdonald, Srivatsan RamanCell Chemical Biology|November 11, 2025
An engineered cysteine sensor optimized for high-throughput screening identifies regulators of intracellular thiol levelsRachel P M Abrams, Rebecca G Donahue, Jessica Ma, et al.Cell Chemical Biology|November 7, 2025
Development of D2HG biosensors inspired by the molecular mechanism of D2HG regulation of DhdRBin Wang, Shouqing Luo, Pengkai SunCell Chemical Biology|November 12, 2025
Lactylation of mTOR enhances autophagy in skeletal muscle during exerciseYan Li, Lamei Xue, Feijie Wang, et al.Cell Chemical Biology|September 19, 2025
Activation primes GPCRs for versatile couplingVsevolod V Gurevich, Eugenia V GurevichCell Chemical Biology|October 24, 2025
Therapeutic targeting of WDR5-MLL1 by EMBOW-derived peptides suppresses leukemia progressionMing Zhang, Meixia Chen, Peiyan Li, et al.Cell Chemical Biology|March 3, 2016
New Insights into the Biosynthetic Logic of Ribosomally Synthesized and Post-translationally Modified Peptide Natural ProductsManuel A Ortega, Wilfred A van der DonkPageof 180