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Cell Death Discovery|July 15, 2025
Epigenetic targeting of MECOM/KRAS axis by JIB-04 impairs tumorigenesis and cisplatin resistance in MECOM-amplified ovarian cancerIbha Singh, Amarnath Karna, Anita Prajapati, et al.Cell Death Discovery|July 16, 2025
Single-cell RNA sequencing reveals the effects of mental stress on mouse mammary tumors and the tumor microenvironmentPengfei Liu, Wenjing Ma, Tao Wang, et al.Cell Death Discovery|July 16, 2025
The EIF4EBP1 gene encoding 4EBP1 is transcriptionally upregulated by MYC and linked to shorter survival in medulloblastomaLaura Hruby, Katerina Schaal, Alberto Delaidelli, et al.Cell Death Discovery|December 30, 2025
Multidimensional regulatory roles and therapeutic applications of SRSF7 in cancerYuan Li, Huimeng Gao, Xuanyu Zhang, et al.Cell Death Discovery|December 22, 2025
FGF1-FGFR2 axis regulated by nuclear receptor RORγ represents an effective strategy in intrahepatic cholangiocarcinomaZhanfeng Gu, Xiaojuan Wang, Hong Wang, et al.Cell Death Discovery|December 15, 2025
The chaperone GRP94 interacts with the proprotein convertase furin and regulates TGF-beta maturation in human primary M2 macrophagesValentin Baverel, Fangmin Wang, Carmen Garrido, et al.Cell Death Discovery|December 12, 2025
Disulfiram activates autophagy via proteasome inhibition and c-Fos/beclin-1 upregulation, synergizing with chloroquineKejin Wang, Zhen Wang, Wenxuan Peng, et al.Cell Death Discovery|December 10, 2025
Circulating tumor cells in breast cancer bone metastasis: mechanisms, clinical relevance, and future directionsLingfeng Ma, Yufei Wang, Shuying Qiu, et al.Cell Death Discovery|December 8, 2025
IL-1β+ lung-resident macrophages mediate endothelial dysfunction and acute lung injury in sepsis through immune-metabolic crosstalkYang Dong, Tianyuan Li, Bei Fang, et al.Cell Death Discovery|December 11, 2025
The inhibition of de novo purine synthesis increases LAMP2 expression to preserve cell viabilityAngela De Cristofaro, Serena Castelli, Federica Felice, et al.Pageof 328