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Chemmedchem|August 15, 2026
Structural and Biophysical Characterization of C-Glycosylic 1,2-Thiodisaccharides Reveals Determinants of Selective Binding to Galectin-7 and Galectin-8NAnastasia S Tsagkarakou, Anastassia L Kantsadi, Vasiliki I Theodoridou, et al.
Chemmedchem|September 5, 2026
Covalent Targeting and Thermostabilization of Oncogenic R280K and R273H Mutants p53 by Small Molecule RVJB59Ricardo J F Ferreira, Lídia M Gonçalves, Mattia Mori, et al.
Chemmedchem|July 24, 2026
Influence of N-Functionalization of Amiridine on the Biological Activity of Its Conjugates as Multitarget Agents for Potential Treatment of Alzheimer's DiseaseGalina F Makhaeva, Tatiana Y Astakhova, Maria V Grishchenko, et al.
Chemmedchem|July 16, 2026
Advances in Tricyclic Compounds for the Treatment of Alzheimer's DiseaseYichun Shi, Xindan Liao, Guangjun Yu
Chemmedchem|July 26, 2026
Synthesis and Biological Activity of Novel Aromatic Aminopropyl Lactams in Two Cancer Cell ModelsM Margarida Martins, Ruben Valente, Ruben Amaro, et al.
Chemmedchem|August 26, 2026
Sulfonylurea Bioisosteres of Sulfonic Acid in JFD 00458-Based ST6GAL1 Inhibitors Enhance Membrane PermeabilityNatan Koraj, Sushmaa Dangudubiyyam, Adelyn M Betances-Mora, et al.
Chemmedchem|August 26, 2026
Investigating the Binding Mode of a Naphthol-Based Inhibitor Targeting SARS-CoV-2 Main ProteaseIfigeneia Akrani, Haifa El Kilani, Franck Touret, et al.
Chemmedchem|September 1, 2026
The Pyrazolone Scaffold: A Privileged Motif for Molecular Hybridization in Drug DiscoveryKe Tang, Yao Liu, Jingning Luo, et al.
Chemmedchem|September 1, 2026
Structure-Guided Optimization of PDE9A Inhibitors Tackling Neuroinflammation: A Combined Computational and In Vitro StudyGiovanni Ribaudo, Elisa Landucci, Margrate Anyanwu, et al.
Chemmedchem|September 1, 2026
Identification of New Putative Autotaxin Inhibitors via Structure-Based Virtual Screening and Evaluation of Their Antiproliferative Properties Against Ovarian and Breast Cancer CellsAngelina Boccarelli, Adriana Coricello, Francesca Alessandra Ambrosio, et al.
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