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Clinical and Translational Medicine|January 6, 2026
MUC4 mutations promote a thrombotic phenotype in patients with paroxysmal nocturnal haemoglobinuria by increasing the deposition of terminal complementYingying Chen, Mengting Che, Chaomeng Wang, et al.Clinical and Translational Medicine|February 2, 2026
Beyond bacterial defences: the role of lysozyme in cancerLei Wang, Qian Dong, Fuchu He, et al.Clinical and Translational Medicine|January 28, 2026
DNTTIP1 drives leukaemogenesis through MiDAC-mediated epigenetic silencing of BMFRuolin Xiu, Yuzhu Ma, Yueying Gao, et al.Clinical and Translational Medicine|February 3, 2026
T-cell exhaustion from a multiomics perspective: Differentiation mechanisms and regulatory networks in the journey from progenitor-Exhausted T cells to terminally exhausted T cellsTong Zhu, Xiaoyu Teng, Qinlian Jiao, et al.Clinical and Translational Medicine|February 8, 2026
Integrative cross-tissue and spatially resolved single-cell profiling uncovers tumour-educated inflammatory remodelling of tissue-resident macrophage ecosystem with immunotherapeutic prognostic significance in pan-cancerWeikai Wang, Zibin Chen, Yuhan Huang, et al.Clinical and Translational Medicine|February 5, 2026
Single-cell analysis reveals cytotoxic and memory CD8+ T cells associated with prolonged survival in relapsed/refractory leukaemia patients after haplo+cord haematopoietic stem cell transplantationHua Li, Zheyang Zhang, Ming Zhu, et al.Clinical and Translational Medicine|December 12, 2025
Comprehensive multi-omics mapping of immune perturbations in autism spectrum disorderChun Yan, Fangmei Feng, Chaoting Lan, et al.Clinical and Translational Medicine|December 12, 2025
Oncofetal dual‑specificity phosphatase 9 drives stem-like properties through ERK1/2-PPARG-SCD axis-mediated lipid metabolism in hepatocellular carcinomaWang Peng, Hai Huang, Yuchong Zhao, et al.Clinical and Translational Medicine|November 26, 2025
CAR-DC combined with CAR-T therapy for relapsed/refractory acute myeloid leukaemia: Research progress and future perspectivesRui Zhang, Jinlin Zhang, Hongkai Zhang, et al.Clinical and Translational Medicine|November 23, 2025
Single-cell landscape of the tumour immune microenvironment in human gynaecologic malignanciesSimin Yin, Sen Li, Mengyan Tu, et al.Pageof 165