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Clinical and Translational Science|November 13, 2025
Representation of Older Adult Patients in Clinical TrialsSebastian Haertter, Navita L Mallalieu, Soundos Saleh, et al.
Clinical and Translational Science|November 10, 2025
Predicting the Pharmacokinetics of T-Cell Engagers as a Function of Target-Mediated Drug DispositionMark Penney, Alberto Ippolito, Elisa Fevola, et al.
Clinical and Translational Science|October 23, 2025
A Comparison of AI and Population PK Models to Predict the Concentrations of Antiepileptic Drugs Using Therapeutic Drug Monitoring RecordsTae Kyu Chung, Howard Lee
Clinical and Translational Science|July 21, 2025
Linkage Between Hemoglobin to High Density Lipoprotein-Cholesterol Ratio and Metabolic Dysfunction-Associated Steatotic Liver Disease: A Nationally Representative StudyZhiping Liu, Huifen Yin, Wenhao Li, et al.
Clinical and Translational Science|July 18, 2025
Sensitivity of Tepotinib to Inhibitors or Inducers of CYP3A4 and P-Gp: Drug Interaction Studies and Physiologically-Based Pharmacokinetic AnalysisRainer Strotmann, Christian Lüpfert, Axel Krebs-Brown, et al.
Clinical and Translational Science|July 17, 2025
Quantifying Risk of Delayed QT Prolongation of Ipatasertib in Preclinical and Clinical Studies in Cancer PatientsVictor Poon, Dhruvitkumar Sutaria, Rodney Prell, et al.
Clinical and Translational Science|July 14, 2025
Sacituzumab Govitecan Population Pharmacokinetics: Updated Analyses Using HR+/HER2- Metastatic Breast Cancer Data From the Phase 3 TROPiCS-02 TrialAbhishek G Sathe, Aksana K Jones, Paul M Diderichsen, et al.
Clinical and Translational Science|July 3, 2025
Methods of Estimating Plasma Pharmacokinetics From Minimally Invasive, High Temporal Resolution Measurements of Interstitial Fluid Drug ConcentrationsMurat K Erdal, Tod E Kippin, João P Hespanha, et al.
Clinical and Translational Science|July 2, 2025
Dosage Regimen Optimization of Ertapenem Against ESBL-Producing Enterobacterales Infection in Critically Ill Patients Using Monte Carlo SimulationApirat Muangkasem, Wichit Nosoongnoen, Suthida Sririttha, et al.
Clinical and Translational Science|July 7, 2025
Effect of Rifampicin on the Pharmacokinetics of Valemetostat and Its Primary Metabolite: A Phase 1 Study in Healthy ParticipantsMasaya Tachibana, Shunji Matsuki, Akifumi Kurata, et al.
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