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Clinical and Translational Science|August 22, 2024
Pharmacokinetics, pharmacodynamics, and safety of GS-3583, a FLT3 agonist Fc fusion protein, from single-ascending-dose phase I study in healthy participantsAnees M Dauki, Nishanthan Rajakumaraswamy, Torsten Trowe, et al.
Clinical and Translational Science|December 2, 2024
Risk of artery dissection during systemic exposure to vascular endothelial growth factor pathway inhibitorsJun Okui, Takashi Waki, Kazuhiro Kajiyama, et al.
Clinical and Translational Science|October 28, 2024
Practical guide to SHAP analysis: Explaining supervised machine learning model predictions in drug developmentAna Victoria Ponce-Bobadilla, Vanessa Schmitt, Corinna S Maier, et al.
Clinical and Translational Science|November 15, 2024
Accumulation of endogenous Muse cells in the myocardium and its pathophysiological role in patients with fulminant myocarditisShigeru Toyoda, Masashi Sakuma, Kazuyuki Ishida, et al.
Clinical and Translational Science|November 4, 2024
A first-in-human, randomized study of the safety, pharmacokinetics and pharmacodynamics of povetacicept, an enhanced dual BAFF/APRIL antagonist, in healthy adultsRupert Davies, Stanford L Peng, Jason Lickliter, et al.
Clinical and Translational Science|August 9, 2024
Using exploratory pharmacokinetic and pharmacodynamic analyses to predict the probability of flu-like symptoms in healthy volunteers and patients with chronic hepatitis B treated with the toll-like receptor 7 agonist ruzotolimodQiudi Jiang, Yuchen Zhang, Dan Duan, et al.
Clinical and Translational Science|July 16, 2024
Inflammation altered correlation between CYP2C19 genotype and CYP2C19 activity in patients receiving voriconazoleSylvia D Klomp, Anette Veringa, Jan-Willem C Alffenaar, et al.
Clinical and Translational Science|July 17, 2024
Reduced hepatic impairment study to evaluate pharmacokinetics and safety of zavegepant and to inform dosing recommendation for hepatic impairmentRajinder Bhardwaj, Mary K Donohue, Jennifer Madonia, et al.
Clinical and Translational Science|July 9, 2024
The interactive walkway provides fit-for-purpose fall-risk biomarkers in the elderly: Comparison of zolpidem and suvorexantIngrid Koopmans, Daphne Geerse, Lara de Ridder, et al.
Clinical and Translational Science|August 2, 2024
A case study of inclusion of rural populations in research: Implications for science and health equityDevon Noonan, Wendy K K Lam, James Goodrich, et al.
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