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Clinical and Translational Science|April 19, 2022
A phase I randomized, double-blind, single subcutaneous dose escalation study to determine the safety, tolerability, and pharmacokinetics of rezafungin in healthy adult subjectsKenan Gu, Dennis Ruff, Cassandra Key, et al.
Clinical and Translational Science|June 30, 2019
Dose Finding in the Clinical Development of 60 US Food and Drug Administration-Approved Drugs Compared With Learning vs. Confirming RecommendationsYassine Kamal Lyauk, Daniël Martijn Jonker, Trine Meldgaard Lund
Clinical and Translational Science|July 4, 2019
A Modeling Framework to Characterize Cytokine Release upon T-Cell-Engaging Bispecific Antibody Treatment: Methodology and OpportunitiesXiaoying Chen, Cris Kamperschroer, Gilbert Wong, et al.
Clinical and Translational Science|October 11, 2019
Target-Mediated Drug Disposition Pharmacokinetic/Pharmacodynamic Model-Informed Dose Selection for the First-in-Human Study of AVB-S6-500Laura Bonifacio, Michael Dodds, David Prohaska, et al.
Clinical and Translational Science|February 10, 2022
Hepatoprotective effects of semaglutide, lanifibranor and dietary intervention in the GAN diet-induced obese and biopsy-confirmed mouse model of NASHMathias B Møllerhøj, Sanne S Veidal, Kirstine Tølbøl Thrane, et al.
Clinical and Translational Science|November 3, 2021
Rituximab exposure-response in triweekly R-CHOP treatment in DLBCL: A loading dose is recommended to improve clinical outcomesShu Liu, Zhao Wang, Rongxin Chen, et al.
Clinical and Translational Science|February 14, 2022
A phase I evaluation of the effect of curcumin on dose-limiting toxicity and pharmacokinetics of irinotecan in participants with solid tumorsOlumide B Gbolahan, Bert H O'Neil, Autumn J McRee, et al.
Clinical and Translational Science|February 16, 2022
Effect of food on capsule and granule formulations of selumetinibSarit Cohen-Rabbie, Alexandra Mattinson, Karen So, et al.
Clinical and Translational Science|March 17, 2022
Pediatric growth patterns in youth-onset type 2 diabetes mellitus: Implications for physiologically-based pharmacokinetic modelsChelsea M Hosey, Kelsee Halpin, Valentina Shakhnovich, et al.
Clinical and Translational Science|February 25, 2022
Impact of disease-modifying therapies on humoral and cellular immune-responses following SARS-CoV-2 vaccination in MS patientsSusan Trümpelmann, Andreas Schulte-Mecklenbeck, Olga V Steinberg, et al.
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