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Clinical Pharmacology and Therapeutics|May 24, 2016
Exome sequencing of extreme clopidogrel response phenotypes identifies B4GALT2 as a determinant of on-treatment platelet reactivityS A Scott, J-P Collet, U Baber, et al.Clinical Pharmacology and Therapeutics|August 12, 2015
Mechanistic understanding of the nonlinear pharmacokinetics and intersubject variability of simeprevir: A PBPK-guided drug development approachJ Snoeys, M Beumont, M Monshouwer, et al.Clinical Pharmacology and Therapeutics|August 12, 2015
Structured Frameworks to Increase the Transparency of the Assessment of Benefits and Risks of Medicines: Current Status and Possible Future DirectionsF Pignatti, D Ashby, E P Brass, et al.Clinical Pharmacology and Therapeutics|August 13, 2015
Therapeutic drug monitoring of monoclonal antibodies in inflammatory and malignant disease: Translating TNF-α experience to oncologyT H Oude Munnink, M J Henstra, L I Segerink, et al.Clinical Pharmacology and Therapeutics|August 13, 2015
Genotyping of a family with a novel deleterious DPYD mutation supports the pretherapeutic screening of DPD deficiency with dihydrouracil/uracil ratioF Thomas, I Hennebelle, C Delmas, et al.Clinical Pharmacology and Therapeutics|March 8, 2016
Improved Prediction of Drug-Induced Torsades de Pointes Through Simulations of Dynamics and Machine Learning AlgorithmsM Cummins Lancaster, E A SobieClinical Pharmacology and Therapeutics|May 22, 2012
Healthy volunteer registries and ethical research principlesE A Kupetsky-Rincon, W K KraftClinical Pharmacology and Therapeutics|July 23, 2013
Regulatory challenges in the review of data from global clinical trials: the PMDA perspectiveK Asano, A Tanaka, T Sato, et al.Clinical Pharmacology and Therapeutics|November 20, 2012
Epigenetics: a new link toward understanding human disease and drug responseA M Cressman, M Piquette-MillerClinical Pharmacology and Therapeutics|August 23, 2014
Cytochrome P450 epoxygenase dependence of opioid analgesia: fluconazole does not interfere with remifentanil-mediated analgesia in human subjectsB G Oertel, J Vermehren, T T Huynh, et al.Pageof 940