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Clinical Pharmacology in Drug Development|September 6, 2022
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Oral NLRP3 Inflammasome Inhibitor ZYIL1: First-in-Human Phase 1 Studies (Single Ascending Dose and Multiple Ascending Dose)Deven V Parmar, Kevinkumar A Kansagra, Taufik Momin, et al.
Clinical Pharmacology in Drug Development|December 18, 2021
Pharmacokinetics, Safety, and Pharmacodynamics of Romiplostim in Chinese Subjects With Immune Thrombocytopenia: A Phase I/II TrialJunyuan Qi, Li Zheng, Bei Hu, et al.
Clinical Pharmacology in Drug Development|October 22, 2021
Lack of a Clinically Meaningful Drug Interaction Between the HIV-1 Antiretroviral Agents Islatravir, Dolutegravir, and Tenofovir Disoproxil FumarateDeanne Jackson Rudd, Saijuan Zhang, Kerry L Fillgrove, et al.
Clinical Pharmacology in Drug Development|February 21, 2022
Assessment of Effects of Investigational TAK-931, an Oral Cell Division Cycle 7 Kinase Inhibitor on the QTc Intervals in Patients With Advanced Solid TumorsXiaofei Zhou, Paul Matthias Diderichsen, Neeraj Gupta
Clinical Pharmacology in Drug Development|February 16, 2022
Pharmacokinetics and Macrophage Inhibitory Cytokine-1 Pharmacodynamics of the Murine Double Minute 2 Inhibitor, Navtemadlin (KRT-232) in Fed and Fasted Healthy SubjectsShekman Wong, Cecile Krejsa, Dana Lee, et al.
Clinical Pharmacology in Drug Development|February 19, 2022
Pharmacokinetics and Safety of the Nucleoside Analog Antiviral Drug Galidesivir Administered to Healthy Adult SubjectsAmanda Mathis, David Collins, Sylvia Dobo, et al.
Clinical Pharmacology in Drug Development|February 19, 2022
Lack of Electrocardiographic Effects of Deucravacitinib in Healthy SubjectsAnjaneya Chimalakonda, Shalabh Singhal, Raymond Darbenzio, et al.
Clinical Pharmacology in Drug Development|February 19, 2022
Effect of Roxadustat on the Pharmacokinetics of Simvastatin, Rosuvastatin, and Atorvastatin in Healthy Subjects: Results From 3 Phase 1, Open-Label, 1-Sequence, Crossover StudiesDorien Groenendaal-van de Meent, Martin den Adel, Virginie Kerbusch, et al.
Clinical Pharmacology in Drug Development|October 17, 2018
Pharmacokinetics of Tenofovir Alafenamide, Tenofovir, and Emtricitabine Following Administration of Coformulated Emtricitabine/Tenofovir Alafenamide in Healthy Japanese SubjectsHiroyuki Yamada, Takuma Yonemura, Takanori Nemoto, et al.
Clinical Pharmacology in Drug Development|March 19, 2022
P-Glycoprotein and Breast Cancer Resistance Protein Transporter Inhibition by Cyclosporine and Quinidine on the Pharmacokinetics of Oral Rimegepant in Healthy SubjectsRajinder Bhardwaj, Julie L Collins, Joseph Stringfellow, et al.
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