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Clinical Pharmacology in Drug Development|August 12, 2024
Effect of Itraconazole, a CYP3A4 Inhibitor, and Rifampin, a CYP3A4 Inducer, on the Pharmacokinetics of VatiquinoneLucy Lee, Martin Thoolen, Jiyuan Ma, et al.
Clinical Pharmacology in Drug Development|August 9, 2024
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Muscarinic M3 Receptor-Positive Allosteric Modulator ASP8302 Following Single and Multiple Ascending Oral Doses in Healthy VolunteersShin Takusagawa, Nicoline Treijtel, Masako Saito, et al.
Clinical Pharmacology in Drug Development|August 5, 2024
Absorption, Metabolism, and Excretion of [14C]-Labeled Anaprazole: A New Proton Pump Inhibitor, After a Single Oral Administration in Healthy Chinese Male SubjectsLijun Xie, Yanjun Xu, Wei Liu, et al.
Clinical Pharmacology in Drug Development|July 16, 2024
Population Pharmacokinetics and Exposure-Response Relationship of Zimberelimab in Chinese Patients with Advanced TumorsFang Yang, Yongying Lu, Lihui Bai, et al.
Clinical Pharmacology in Drug Development|July 24, 2024
Effect of Erdafitinib on the Pharmacokinetics of Midazolam and Metformin in Patients With Advanced Solid Tumors Harboring FGFR Gene AlterationsWei Zhu, Mahadi Baig, Vahid Naini, et al.
Clinical Pharmacology in Drug Development|July 2, 2024
SERENE ER Analysis Part 2 SERENE-UC: Exposure-response Analysis of Higher Versus Standard Adalimumab Dosing Regimens for Patients with Moderately to Severely Active Ulcerative ColitisSven Stodtmann, Mong-Jen Chen, Ana Victoria Ponce-Bobadilla, et al.
Clinical Pharmacology in Drug Development|July 12, 2024
Effect of a High-Fat Meal on the Pharmacokinetics of an Immediate Release Atogepant TabletRamesh R Boinpally, Joel M Trugman
Clinical Pharmacology in Drug Development|July 12, 2024
Effect of Mild or Moderate Hepatic Impairment on the Pharmacokinetics of Avacopan, a Small-Molecule Complement C5a Receptor Antagonist, for the Treatment of Antineutrophil Cytoplasmic Autoantibody-Associated VasculitisShichang Miao, Pablo Suso, John A Furst, et al.
Clinical Pharmacology in Drug Development|August 19, 2024
Pharmacokinetics and Safety of Linezolid Tablets of 2 Different Manufacturers in Healthy Chinese Subjects in Fasting and Fed StatesHanjing Chen, Hongrong Xu, Fei Yuan, et al.
Clinical Pharmacology in Drug Development|June 20, 2024
Impact of Food on the Oral Absorption of N-Acetyl-D-Mannosamine in Healthy Men and WomenAllan M Evans, Gianfranco Fornasini, Tahlia R Meola, et al.
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