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Clinical Pharmacology in Drug Development|April 30, 2016
Population pharmacokinetic and pharmacodynamic analysis of plasma Aβ40 and Aβ42 following single oral doses of the BACE1 inhibitor AZD3839 to healthy volunteersAngelica Quartino, Gunilla Huledal, Erik Sparve, et al.
Clinical Pharmacology in Drug Development|April 30, 2016
Pharmacokinetics of rabeprazole granules versus tablets, and the effect of food on the pharmacokinetics of rabeprazole granules in healthy adults-cross-study comparisonAn Thyssen, Bhavna Solanki, Martha Gonzalez, et al.
Clinical Pharmacology in Drug Development|April 30, 2016
The effect of mild and moderate hepatic impairment on the pharmacokinetics of tofacitinib, an orally active Janus kinase inhibitorNervin Lawendy, Manisha Lamba, Gary Chan, et al.
Clinical Pharmacology in Drug Development|April 30, 2016
PRTX-100 and methotrexate in patients with active rheumatoid arthritis: A Phase Ib randomized, double-blind, placebo-controlled, dose-escalation studyEdward Bernton, William Gannon, William Kramer, et al.
Clinical Pharmacology in Drug Development|May 4, 2016
Pharmacokinetic and bioequivalence evaluation of single-tablet and separate-tablet regimens for once-daily cobicistat-boosted elvitegravir in healthy Japanese male subjects: A randomized, two-way crossover studyMari Shiomi, Shunji Matsuki, Atsushi Ikeda, et al.
Clinical Pharmacology in Drug Development|May 4, 2016
Effect of canagliflozin on the pharmacokinetics of glyburide, metformin, and simvastatin in healthy participantsDamayanthi Devineni, Prasarn Manitpisitkul, Joseph Murphy, et al.
Clinical Pharmacology in Drug Development|July 14, 2016
Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of ASP2408, a Potent Selective T-Cell Costimulation Modulator After Single and Multiple Ascending Doses in Healthy Volunteers and RA PatientsTong Zhu, James Keirns, Corrie Howieson, et al.
Clinical Pharmacology in Drug Development|June 15, 2016
Pharmacokinetics of Lidocaine and Its Metabolites Following Vaginal Administration of Lidocaine Gel to Healthy Female SubjectsBridget Martell, Harvey Kushner, Elaine Richardson, et al.
Clinical Pharmacology in Drug Development|June 17, 2016
Phase IA Clinical Trial Evaluating the Tolerability, Pharmacokinetics, and Analgesic Efficacy of an Intrathecally Administered Neurotensin A Analogue in Central Neuropathic Pain Following Spinal Cord InjuryChristine N Sang, Kate J Barnabe, Steven E Kern
Clinical Pharmacology in Drug Development|June 17, 2016
A Phase 1 Dose-Escalation Study of ASP2409, a Selective T-Cell Costimulation Inhibitor, in Stable Rheumatoid Arthritis Patients on Methotrexate TherapyWenhui Zhang, Robert M Kernstock, Erik E Karrer, et al.
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