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Computational and Structural Biotechnology Journal|January 22, 2026
Empirical optimization of dual-sgRNA design for in vivo CRISPR/Cas9-mediated exon deletion in miceSung-Yeon Lee, Seongwon Ma, Sangjun Davie Jeon, et al.Computational and Structural Biotechnology Journal|January 16, 2026
Struct2SL: Synthetic lethality prediction based on AlphaFold2 structure information and Multilayer PerceptronYurui Huang, Ruzhe Yuan, Yaxuan Li, et al.Computational and Structural Biotechnology Journal|January 19, 2026
Developing provider digital twins for personalized provider-patient communication via a RAG-based conversational frameworkPengze Li, Yutong Hu, Jianfu Li, et al.Computational and Structural Biotechnology Journal|January 16, 2026
TMEtyper: A computational method for tumor microenvironment subtyping with applications in immunotherapyYaru Miao, Tong Zhou, Yan Li, et al.Computational and Structural Biotechnology Journal|January 8, 2026
From latent dynamics to data geometry: Nonlinear diffusion modelling for protein structuresXiao Liang, Eric Paquet, Herna Viktor, et al.Computational and Structural Biotechnology Journal|January 16, 2026
RNA-seq-derived sequence variations are excellent features for cell line identificationLisa Müller, Simon Müller, Khursheed Ul Islam Mir, et al.Computational and Structural Biotechnology Journal|January 16, 2026
TBM preferred to AlphaFold 3 for functional models of insect odorant receptorsVaanathi Chidambara Thanu, Amara Jabeen, Spyros E Zographos, et al.Computational and Structural Biotechnology Journal|October 27, 2025
IsomiRome analysis reveals dysregulation of 5' isomiRs during SARS-CoV-2 infectionMing-Ju Amy Lyu, Munire Maimaiti, Ziwei Zhong, et al.Computational and Structural Biotechnology Journal|October 27, 2025
Corrigendum to "A semi-mechanistic mathematical framework for simulating multi-hormone dynamics in reproductive endocrinology" [Comput Struct Biotechnol J 27 (2025) 3654-3662]Alexandre Vallée, Anis Feki, Gaby Moawad, et al.Computational and Structural Biotechnology Journal|October 27, 2025
From single cells to communities: Mathematical perspectives on bacterial quorum sensingSara Sadr, Bahram Zargar, Marc G Aucoin, et al.Pageof 380